EXERCISE TRAINING ON BONE MINERAL DENSITY IN FRAIL OLDER WOMEN AND MEN

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。sir前瞻性研究表明，骨质流失随着年龄的增长而加速，导致骨密度（BMD）显著降低。由于体力活动为骨骼健康提供了机械刺激，老年时的低骨密度可能部分归因于废用性萎缩。一些随机对照试验（RCT）发现，运动可以增加老年人的骨密度，但有一个局限性，即老年人、身体虚弱的人没有被包括在内。本研究的目的是评估多组分运动计划与低强度家庭运动对老年体弱个体骨密度的影响

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. SIR-Prospective studies suggest that bone loss accelerates with advancing age, leading to markedly decreased bone mineral density (BMD). Because physical activity provides the mechanical stimulus for bone health, low BMD in old age may be due, in part, to disuse atrophy. Some randomized controlled trials (RCT) have found that exercise increases BMD in older adults, but a limitation is that older, physically frail individuals were not included. The aim of this study was to evaluate the effects of a multi-component exercise programme, compared with low intensity home exercise, on BMD in older frail individua