NCCU-BBRI/UNC-LINEBERGER PARTNERSHIP IN CANCER RESEARCH

描述(由申请人提供) 朱利叶斯·L·钱伯斯生物医学生物技术研究所 在北卡罗来纳中央大学(NCCU)和北卡罗来纳大学莱恩伯格分校 北卡罗来纳大学综合癌症中心(UNC LCCC) 教堂山(UNC-CH)建议继续有效、可持续和 癌症研究中的互惠伙伴关系，重点是 非洲裔美国人的健康差距。在过去的一年里，有了资金 来自国家癌症研究所，这两个机构坚定地 在互补的体制基础上建立了伙伴关系 在分子和人口科学方面进行联合规划的优势， 并强调一项具体和可行的“门户”倡议：建立 NCCU癌症分子/基因分析核心实验室 研究。该伙伴关系现在提议通过一个 NCI资助的综合少数民族合作计划补助金(U56) 机构/癌症伙伴关系。除了在以下方面继续努力外 分子/基因分析与癌症核心实验室的伙伴关系 将强调一系列相互关联的网关试点举措，同时 技术转让，这导致了一个重大的合作研究项目 (包括外展/健康教育部分)以人群为基础的队列研究 非洲裔美国男性的前列腺癌。这个项目将是一个主要的焦点 综合少数族裔机构/癌症的计划申请情况 中心合作伙伴关系(U54 CMI/CCP)赠款。的特定协作组件 该提案包括：两个试点研究项目(化验开发和 队列发展)；外展和教育试点方案；资源和 加强以JLC-BBRI癌症核心实验室为核心的基础设施； 以及初级教职员工和学生的职业发展。北卡罗来纳大学的莱恩伯格 和北卡罗来纳大学-教堂山提供合作伙伴关系：1)广泛的经验、专业知识、 以及用于癌症研究和培训的资源；以及2)表现出的兴趣 少数族裔的健康差距。JLC-BRI和NCCU提供合作伙伴关系： 1)通过以下途径接触少数群体的经验和专门知识 文化上适当和敏感的干预措施；2)获得 少数民族人口；3)少数民族学生的培训机会 可能对癌症研究领域的职业感兴趣。这些相辅相成 机构优势将有助于伙伴关系：1)建立有效的 癌症研究基础设施/计划和增加培训机会 一个少数群体服务机构；和2)加强以社区和人口为基础 针对少数族裔癌症相关健康差异和增加的研究 在NCI资助的Coin Complete癌症中心培训少数民族科学家 中心。

DESCRIPTION (provided by applicant) The Julius L. Chambers Biomedical Biotechnology Research Institute (UNC LCCC) at North Carolina Central University (NCCU) and the UNC Lineberger Comprehensive Cancer Center (UNC LCCC) at the University of North Carolina at Chapel Hill (UNC-CH) propose to continue an effective, sustainable, and mutually beneficial partnership in cancer research that focuses on African-American health disparities. During the past year and with funding from the National Cancer Institute, the two institutions have firmly established the Partnership by building on complementary institutional strengths conducting joint planning in the molecular and population sciences, and emphasizing a concrete and feasible "gateway" initiative: establishment of an NCCU Cancer Core Laboratory for molecular/genetic analysis in cancer research. The Partnership now proposes to expand its initiatives through an NCI-funded Cooperative Planning Grant (U56) for Comprehensive Minority Institution/Cancer Partnership. In addition to continued efforts in molecular/genetic analysis and the Cancer Core Laboratory, the Partnership will emphasize a series of linked gateway pilot initiatives, accompanied by technology transfer, that lead toward a major collaborative research project (with outreach/health education components) a population-based cohort study of prostate cancer in African-American men. This project will be a major focus of the planned application for a Comprehensive Minority Institution/Cancer Center Partnership (U54 CMI/CCP) grant. Specific collaborative components of the proposal include: two pilot research projects (assay development and cohort development); a pilot program in outreach and education; resource and infrastructure enhancement centering on the JLC-BBRI Cancer Core Laboratory; and career development for junior faculty and students. The UNC Lineberger and UNC-Chapel Hill offer the Partnership: 1) extensive experience, expertise, and resources for cancer research and training; and 2) a demonstrated interest in minority health disparities. The JLC-BBRI and NCCU offer the Partnership: 1) experience and expertise in reaching minority populations through culturally appropriate and sensitive interventions; 2) opportunities to access minority populations; and 3) training opportunities for minority students potentially interested in careers in cancer research. These complementary institutional strengths will help the Partnership: 1) establish an effective cancer research infrastructure/program and increase training opportunities at a minority serving institution; and 2) enhance community- and population-based research targeting minority cancer-related health disparities and increase training of minority scientists at an NCI funded Coin comprehensive Cancer Center.