SIMULTANEOUS MAPPING OF FUNCTIONAL MAPS & AXONAL CONNECTIVITY

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。在同一猫视皮质中进行了基于OLD的功能磁共振成像和扩散张量成像，从而提供了潜在功能激活的轴突环路图。此外，还利用功能磁共振激活灶作为3D DTI纤维重建算法的种子点。从研究中观察到，可以获得与功能磁共振图一致的活体连接图，从而极大地扩展了功能磁共振对认知神经科学的解释能力。本研究开发的方法将为在体神经解剖学和脑发育的无创纵向研究能力奠定基础。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. ?OLD based functional MRI and Diffusion Tensor Imaging were performed in the same cat visual cortex, thus providing the map of the axonal circuitry underlying functional activation. Furthermore, the foci of fMRI activation were utilized as the seeding points for 3D DTI fiber reconstruction algorithms. From the study, it was observed that in vivo connectivity maps can be obtained in concordance with fMRI maps, thus greatly expanding the explanatory power of fMRI for cognitive neurosciences. The methods developed in this study will lay foundation for in vivo neuroanatomy and the ability of non-invasive longitudinal studies of brain development.