Training Program in Transplantation

描述（由申请人提供）： 在过去的6年中，一个充满活力的国际公认的移植研究人员小组已被战略性地招募到路易斯维尔大学，其中许多是经验丰富的成熟团队。 该小组准备建立一个尖端的博士后研究员获得移植生物学计划，以教育下一代科学家。 该提案直接解决了NIH培训补助金计划的使命，以帮助确保多样化和训练有素的劳动力可用于承担与国家生物医学研究议程相关的领导角色。学员将与一名或多名教师进行基础研究，并审核免疫学，干细胞生物学和移植课程。 学员必须具有博士学位。生物化学、免疫学、微生物学、生理学、遗传学和相关领域的博士学位，或D.V.M.或者医学博士并将从该计划的教师收到的申请中选出。 申请人将被要求提交一份简历，出版物清单，3封推荐信，以及一份关于拟议的具体研究的声明。 由项目总监和选定的高级培训师组成的培训委员会将从这些申请中选择学员。 学员将准备，与他们的导师，书面培训计划，包括课程，实验室培训，并将由培训委员会审查和批准的研究说明。 将通过每周与一名或多名培训员举行会议、在每周系列研讨会上介绍研究成果以及书面年度报告来监测受训人员的进展情况，以获得更多年的支助。 受训人员将出版手稿，定期出席研究会议并在会上介绍其工作，并提交外部资助的赠款申请。 培训计划的中心整合重点将是讲座系列，包括每周移植免疫学和干细胞生物学实验室研讨会;每周联合免疫学杂志俱乐部;客座教授系列;移植会议系列;癌症中心化学引诱剂系列;和研究研讨会系列。 这些讲座不仅提供了一个发展演讲技巧的竞技场，而且还提供了一个来自世界各地的移植和相关领域的专家作为演讲者参加的场所。 该培训计划的教师具有成功开展该计划的研究背景，专业知识和设施。 布朗癌症中心的细胞治疗研究所、外科、生理学、生物物理学、医学、分子生物学、心脏病学、儿科学、生物化学、药理学和毒理学、眼科学、微生物学和免疫学、内科学、病理学、神经外科学、解剖科学、医学伦理学、生物统计学和神经生物学等部门都有设备齐全、位于中心位置的实验室。 大多数培训人员也是研究所和中心的成员，这些研究所和中心致力于将具有广泛补充移植兴趣的多学科团体聚集在一起。因此，博士后研究员可以获得各种各样的技术和广泛的培训经验。我们的目标是，经过3年的培训，学员将有资格在工业，学术界和生物技术领域担任与移植和干细胞生物学相关的研究职位。

DESCRIPTION (provided by applicant): Over the past 6 years, a dynamic group of internationally recognized investigators in transplantation have been strategically recruited to the University of Louisville, many as seasoned, established teams. This group is poised to establish a cutting-edge Postdoctoral Research Fellow gaining program in transplantation biology to educate the next generation of scientists. This proposal directly addresses the mission of the NIH training grant program to help ensure that a diverse and highly trained workforce is available to assume leadership roles related to the nation's biomedical research agenda Trainees will undertake basic research with one or more faculty members and audit courses in immunology, stem cell biology, and transplantation. Trainees must have either a Ph.D. in biochemistry, immunology, microbiology, physiology, genetics, and related areas, or a D.V.M. or M.D. and will be selected from applications received by faculty in this program. Applicants will be required to submit a CV, publication list, 3 letters of recommendation, and a statement of the specific research proposed. A Training Committee comprised of the program Director and selected senior trainers will select the trainees from among these applications. Trainees will prepare, with their mentor, a written training plan including coursework, laboratory training, and research description which will be reviewed and approved by the Training Committee. The progress of trainees will be monitored by weekly meetings with one or more trainers, presentation of the research results at the weekly seminar series, and written annual reports for additional years of support. Trainees will be expected to publish manuscripts, regularly attend and present their work at research meetings, and submit grant applications for external funding. A central integrating focus of the training program will be the lecture series comprised of weekly laboratory seminars in transplantation immunology and stem cell biology; weekly joint immunology journal club; visiting professor series; transplant conference series; cancer center chemoattractant series; and the research seminar series. These lectures not only provide an arena to develop presentation skills but also provide a venue in which experts in transplantation and related areas from throughout the world participate as speakers. The faculty in this training program has the research background, expertise, and facilities to successfully conduct this program. Well-equipped, centrally-located laboratories exist at the Institute for Cellular Therapeutics, Brown Cancer Center, and Departments of Surgery, Physiology, Biophysics, Medicine, Molecular Biology, Cardiology, Pediatrics, Biochemistry, Pharmacology and Toxicology, Ophthalmology, Microbiology and Immunology, Internal Medicine, Pathology, Neurological Surgery, Anatomical Sciences, Medical Ethics, Biostatistics, and Neurobiology. Most trainers are also members of Institutes and Centers that serve to bring together multidisciplinary groups with interests that broadly complement transplantation. Postdoctoral fellows therefore have access to a wide variety of techniques and breadth of training experience. It is our goal that after 3 years of training, trainees will be qualified to assume research positions related to transplantation and stem cell biology in industry, academia, and biotechnology.