Research Training in Pediatric Emergency Medicine

描述（由申请人提供）：在过去的6年里，波士顿儿童医院（CHB）的儿科急诊医学部一直是NRSA-T32资助# HD40128-04（儿科急诊医学研究培训）的接受者。此更新申请寻求继续资助一个独特的研究培训企业在儿科急诊医学。研究培训计划建立在CHB急诊科致力于为儿科急诊科医生的研究事业做好准备的基础上，通过严格的临床、信息学和基础科学调查来推进该领域的发展。迄今为止，已有9名研究员参加了这项培训补助金。所有人都作为高产的、有资助的研究者留在了学术医学领域。在最初6年成功的基础上，拟议的延续将维持项目计划，这是项目成功的原因。学员将继续有3个研究方向：临床调查、医学信息学或基础科学。临床调查中的学科将包括临床流行病学、健康结果、生物恐怖主义/应急准备中的循证协议和患者安全。医学信息学的学科将包括数据挖掘和建模、自动化决策支持和综合征监测/公共卫生信息学。基础科学学科将包括细胞和分子生物学、功能基因组学/蛋白质组学/代谢组学、免疫学/炎症学和药理学/毒理学。通过掌握这些学科获得的工具将应用于儿科急诊医学的特定主题。更新建议中有两个重大修改：(1)将研究培训期从2年延长到3年；(2)增加博士后培训生。本申请拟资助6名博士后和博士后研究员。研究培训将继续在CHB/HMS和大波士顿医疗界的一组杰出研究人员的指导下进行。在这个研究培训计划中建立的广泛的、多学科的、多地点的合作将有助于塑造未来的研究团队，这是NIH路线图的既定目标。作为训练有素的内科科学家，该项目的毕业生将成为加快儿科急诊医学这一新生专科知识获取步伐的主要建筑师。

DESCRIPTION (provided by applicant): The Division of Pediatric Emergency Medicine at Children's Hospital Boston (CHB) has been, for the last 6 years, recipient of NRSA-T32 grant # HD40128-04 (Research Training in Pediatric Emergency Medicine). This renewal application seeks continued funding for a unique research training enterprise in pediatric emergency medicine. The Research Training Program was built on the CHB Division of Emergency Medicine's dedication to preparing pediatric emergentologists for research careers that will advance the field through the conduct of rigorous clinical, informatics, and basic science investigation. To date, 9 fellows have entered this Training Grant. All have remained in academic medicine as highly productive, funded investigators. Building on the success of the initial 6 years, the proposed continuation will maintain the Program Plan that has been responsible for the success of the program. Trainees will continue to have 3 research tracks available: clinical investigation, medical informatics, or basic science. The disciplines within clinical investigation will include clinical epidemiology, health outcomes, evidence-based protocols in bioterrorism/emergency preparedness, and patient safety. Disciplines within medical informatics will include data mining and modeling, automated decision support, and syndromic surveillance/public health informatics. Disciplines within basic science will include cellular and molecular biology, functional genomics/proteomics/ metabolomics, immunology/inflammation, and pharmacology/toxicology. The tools acquired through mastery of these disciplines will be applied to specific themes in pediatric emergency medicine. Two significant revisions are found in this renewal proposal: (1) extension of the research training period from two to three years, and (2) the addition of post-doctoral trainees. This application proposes funding for 6 post-residency and post-doctoral fellows. Research training will continue to take place under the mentorship of a group of outstanding investigators in the CHB/HMS and Greater Boston medical community. The broad, multidisciplinary, multi-site collaborations built within this Research Training Program will help to shape the research teams of the future, an established goal of the NIH Roadmap. Graduates of the Program, as well-trained physician-scientists, will be the chief architects in accelerating the pace of knowledge acquisition in the nascent subspecialty of pediatric emergency medicine.