Translational Research Training Program in Gerontology and Geriatrics

描述（由申请人提供）：约翰霍普金斯大学医学院老年医学和老年医学研究培训计划的主要目标是教育和培训具有医学博士学位的合格个人，使其成为老年医学和老年医学的独立研究者。在奖学金培训结束时，候选人将为在大学医学中心的老年医学部门从事生物医学和衰老临床研究的学术生涯做好充分的准备。为了培养下一代的独立科学家和临床研究者，他们将站在衰老转化研究的前沿，受训者要学习十项基本技能；完成一门核心课程，包括以下正式课程：(1)临床研究设计与分析，(2)衰老研究的理论框架/分子机制，以及(3)人类衰老的生物学/生理学；并参与“360度翻译项目”，由多学科研究生组成的团队确定和调查与老龄化相关的重要研究领域，这些领域可以在科学研究方法和临床实践之间进行翻译。此外，研究员在约翰霍普金斯大学全职教师的指导下，经常与老年学研究中心（GRC）的高级工作人员合作，参与早期和广泛的实验室和临床研究培训，GRC是国家老龄研究所（NIA）的主要校内研究项目。这种指导的研究经历包括与老年病学/老年学项目教师的结构化会议，以及根据受训者的经验和兴趣量身定制的监督研究项目，目标是产生一篇或多篇第一作者，同行评审的出版物和一份资助申请，以支持进一步的研究。在美国和世界老年人的比例不断增长，需要培训未来的研究人员在老年学和老年病学。这份修订后的申请是为该项目申请额外五年的资金，其目标是培养未来的研究人员和学术领袖，他们将促进将基础科学知识转化为护理和政策标准，以应对改善老年人健康的挑战。

DESCRIPTION (provided by applicant): The primary objective of the Research Training Program in Gerontology and Geriatrics at the Johns Hopkins University School of Medicine is to educate and train qualified individuals with MD and/or PhD degrees to become independent investigators in geriatric medicine and gerontology. By the end of fellowship training, candidates are rigorously prepared for success in embarking on academic careers in biomedical and clinical research in aging within a geriatrics division of a university medical center. In order to train the next generation of independent scientists and clinical investigators who will be at the forefront of translational research on aging, trainees learn ten essential skill sets; complete a core curriculum which includes formal courses addressing (1) clinical study design and analysis, (2) the theoretical framework/molecular mechanisms underlying research on aging, and (3) the biology/physiology of aging in humans; and participate in a "360-degree Translation Project" where a team of multidisciplinary postgraduate fellows identify and investigate important aging-related research areas that are ready for translation between scientific methodologies for investigation as well as clinical practice. Additionally, fellows experience early and extensive involvement in laboratory and clinical research training under the tutelage of full-time faculty members at Johns Hopkins, often in collaboration with senior staff of the Gerontology Research Center (GRC), the major intramural research program of the National Institute on Aging (NIA). This mentored research experience includes structured meetings with Program Faculty in geriatrics/gerontology and a supervised research project tailored to the trainee's experiences and interests, with the goal of producing one or more first-authored, peer-reviewed publications and a grant application to support further research. The growing proportion of older adults in the United States and the world underlies the need to train future researchers in Gerontology and Geriatrics. This revised application is a request for an additional five years of funding for this program, whose goal is to prepare the future researchers and academic leaders who will facilitate the translation of basic scientific knowledge to standards of care and policy in order to meet the challenge of improving the health of the elderly.