Systematic Review: Measures of Sexual Quality of Life for Female Cancer Survivors

描述（由申请人提供）：女性一生中有三分之一的机会患上癌症。随着生存率的不断上升，越来越多的妇女患有癌症。作为回应，临床研究人员专注于癌症幸存者的生活质量问题，如性生活质量（SQoL）。性和亲密关系已被证明在长期生存中发挥重要作用。然而，越来越多的关注是，SQOL的结构尚未充分测量女性癌症幸存者，包括女性性反应，生育能力和绝经状态。拟议的项目旨在解决关键问题的概念化和测量的SQOL的女性癌症幸存者使用系统的审查技术。具体目标是：（1）回顾女性SQOL的领域如何因癌症部位、生存阶段、生命阶段和伴侣/配偶的存在而变化;（2）评估女性SQOL研究的质量;（3）通过回顾和识别现有自我报告评估工具中的项目差距，描述如何测量女性癌症幸存者的SQOL;（4）确定研究人员和医生需要了解的关于妇女性生活质量的癌症特有和性别特有的问题。使用系统性文献综述的原则，我们将对已发表和未发表的文献进行彻底检索。SQoL被广泛定义为包括性功能和性功能障碍，性满意度和性健康。样本中的每项合格研究将根据许多特征进行编码，例如研究设置、受试者、方法和研究质量。将严格制定编码程序，以保持有效性和可靠性。我们还将系统地分析项目、子量表和量表水平上的大约75种评估工具，以记录项目差距，即，内容上的重大疏忽。我们的分析将包括，但超越，传统的心理测量的可靠性和有效性评估。使用系统的编码系统，我们已经开发和试点，我们将编码项目的内容，以评估如何SQoL领域已经解决。研究结果将提供用于评估女性癌症幸存者SQOL的可用措施和项目的优点和缺点的明确总结。

DESCRIPTION (provided by applicant): There is a 1 in 3 chance that a woman will develop cancer in her lifetime. As survival rates continue to rise, growing numbers of women are living with cancer. In response, clinical researchers have focused on quality of life issues for cancer survivors, such as sexual quality of life (SQoL). Sexuality and intimacy have been shown to play important roles in long-term survivorship. However, there is growing concern that the construct of SQoL has not been adequately measured for female cancer survivors, including female sexual response, fertility, and menopausal status. The proposed project aims to address key questions regarding the conceptualization and measurement of SQoL for female cancer survivors using systematic review techniques. The specific aims are: (1) To review how the domain of female SQoL varies by cancer site, stage of survivorship, life stage, and the presence of a partner/spouse; (2) To assess the quality of the research on female SQoL; (3) To describe how SQoL has been measured for female cancer survivors by reviewing and identifying item gaps in existing self-report assessment tools; (4) To identify cancer-specific and gender-specific concerns that researchers and physicians need to be informed about concerning women's sexual quality of life. Using the principles of systematic literature review, we will undertake a thorough search of the published and unpublished literature. SQoL is broadly defined to include sexual function and dysfunction, sexual satisfaction, and sexual health. Each eligible study in the sample will be coded with respect to a number of features, such as the setting of the study, participants, methodology, and study quality. Coding procedures will be rigorously developed to maintain validity and reliability. We will also systematically analyze approximately 75 assessment tools on the item, subscale, and scale levels to document item gaps, i.e., a significant oversight in content. Our analysis will include, but go beyond, traditional psychometric assessments of reliability and validity. Using a systematic coding system that we have developed and piloted, we will code item content in order to evaluate how the domain of SQoL has been addressed. The findings will provide a clear summary of the strengths and weaknesses of available measures and items used to assess SQoL among female cancer survivors.