BioMEMS From Research Discovery to Technology to Clinic

本次专题会议/研讨会的主要目标将是协同多学科研究团队并促进微机电系统的生物医学应用-微电子，微制造和微加工技术统称为MEMS（及其扩展到纳米级（NEMS），芯片实验室和微总体分析系统）-改变疾病诊断，治疗和预防的临床基础。该专题会议将于2008年10月19日至24日在马萨诸塞州波士顿举行的第55届AVS国际研讨会和展览中举行，将展示新兴的“生物医学系统”领域的积累证据、最先进的方法和创新设计，其中包括用于诊断和治疗应用的微纳米级设备或系统。在主题会议结束时，将有一个为期半天的研讨会，专门讨论优先研究机会和临床应用与基础研究之间的障碍，这些障碍使得生物医学系统难以转化为临床，而临床需求又难以转化为制造平台。这些障碍限制了人们对该领域的兴趣，并阻碍了临床研究企业在本可以以比现在更快的速度扩张的时候。会议/研讨会将包括新的和有经验的研究人员，并将结合正式演讲和非正式讨论，以传达化学，生物学，物理学和工程学以及材料科学，制造，电动力学，流体学和电子学在微观和纳米尺度上的前沿进展的优点和巨大的兴奋，这将加速生物医学系统的发展，以改善诊断，监测，跨多器官系统的人类疾病中生物系统的控制和治疗。美国国立卫生研究院提出的这项努力将为增加年轻研究人员和代表性不足的少数民族的参与提供资金，考虑到未来20年可能被利用的许多机会，这是一项及时的投资。虽然研讨会的主要目标是提供关于如何更快地将生物医学ems纳入医学/健康应用的新见解，但也将关注与其他联邦任务导向机构相关的潜在衍生应用，包括环境（EPA），空间医学（NASA）和化学/生物防御（DOD， DHS）。这些其他机构的投资将增加NIH开发生物医学系统的任何项目。

The major objective of this topical conference / workshop will be to synergize multidisciplinary research teams and to catalyze the biomedical applications of microelectromechanical systems - the microelectronics, microfabrication and micromachining technologies known collectively as MEMS (and its extension to the nanoscale (NEMS), Lab-on-a-Chip, and micro total analysis systems) - to change the clinical foundations of disease diagnosis, treatment and prevention. The topical conference - embedded in the 55th AVS International Symposium and Exhibition, 19-24 October 2008, Boston MA - will present accumulating evidence, state-of-the-art methodologies, and innovative designs in the emerging field of 'BioMEMS,' which includes micro- and nanoscale devices or systems fabricated for diagnostic and therapeutic applications. At the end of the topical conference, there will be a half-day workshop that will specifically address prioritized research opportunities and barriers between clinical application and basic research that make it difficult to translate BioMEMS to the clinic - and clinical needs back to the fabrication bench. These barriers are limiting interest in the field and hampering the clinical research enterprise at a time when it could be expanding much faster than it is. The conference/workshop will include both new and experienced investigators, and will combine formal presentations and informal discussions to convey the merits and tremendous excitement of cutting edge advances in chemistry, biology, physics and engineering - as well as materials science, fabrication, electrokinetics, fluidics and electronics at the micro- and nanoscale - that will accelerate the development of BioMEMS to improve the diagnosis, monitoring, control and treatment of biological systems perturbed in human diseases across multiple organ systems. This NIH proposed effort will provide funds for augmenting the participation of young investigators and underrepresented minorities, a timely investment given the many opportunities that might be exploited over the next 20 years. While the principle workshop goal is to provide new insights into how BioMEMS will be more rapidly incorporated into medicine/health applications, there will be attention to potential spin out applications pertinent to other Federal mission oriented agencies including environment (EPA), space medicine (NASA), and chem/bio defense (DOD, DHS). Investments by these other agencies will augment any NIH programs to exploit BioMEMS.