BioPAX - Biological Pathway Community Workshop

通路信息对于理解生物系统至关重要。不幸的是，上线的170多人 途径数据资源在生物过程的覆盖和表示方面差异很大，使得它们的 用来解决生物问题难度极大。BioPAX基团由该途径形成 数据库社区在2002年11月开发了一种标准生物途径数据交换格式，以 通过一系列的小研讨会来解决这个问题。这导致了社区的发展 公认的开源BioPAX Level 1交换格式，支持代谢途径数据和 BioPAX Level 2，增加了对分子相互作用数据的支持。我们为一系列研讨会寻求支持 2006年、2007年和2008年。本系列会议的目标是扩展BioPAX数据模型 通过增加对信号通路、基因调控网络和遗传相互作用的支持，例如 上位论；增加对.BioPAX的数据库和工具支持；并鼓励公共 可获得的路径数据及其在生物学问题中的应用。我们建议举办BioPAX研讨会 一年两次，每次两天。这些将侧重于通过BioPAX数据模型实现我们的目标 和社区发展讨论。每年一次的研讨会将包括一个研讨会，邀请 演讲者讨论他们与计算研究相关的途径。会议将包括阿卡克松， 在那里协作开发计算机软件，例如数据库转换器。会议将是 由参与者和地点主办，将在加利福尼亚州门洛帕克的SRI(Peter Karp)、冷泉骑行 港湾实验室，纽约(林肯·斯坦)和纪念-斯隆·凯特琳癌症中心，纽约 (克里斯·桑德)或其他方便的美国地点。所有会议都将开放给社区参与，并 所有会议纪要和由此产生的工作都可以通过www.Bioax.org网站以开放源码条款免费获得。

Pathway information is vital for understanding biological systems. Unfortunately,the over 170 online pathway data resourcesvary widely in coverage and representation of biological processes, making their use for biological problem solving extremely difficult. The BioPAX groupwas formed by the pathway database community in November 2002 to develop a standard biological pathway data exchangeformat to solve this issue through a series of small workshops. This has resulted in the development of the community accepted, open-source BioPAX level 1 exchange format, which supports metabolic pathway data and BioPAX level 2, which adds support for molecular interaction data. We seek support for a workshop series for the years 2006, 2007 and 2008. The goals of this meeting series are to expandthe BioPAX data model by adding support for signaling pathways, gene regulation networks and genetic interactions, such as epistasis; to increase database and tool support for.BioPAX; and to encourage the growth of publicly accessible pathway data and its application to biological problems. We propose to hold BioPAX workshops twice a year, each lasting two days. These will focus on achieving our goals through BioPAX data model and community development discussions. One workshop per year will include a symposium of invited speakers discussing their pathway related computational research. Meetings will include ahackathon, where computer software, such as database converters, is collaboratively developed. Meetings will be hosted by participants and locationswill cycle through SRI, Menlo Park, CA (Peter Karp), Cold Spring Harbor Labs, New York, NY (Lincoln Stein) and Memorial-Sloan Kettering Cancer Center, New York, NY (Chris Sander) or other convenient US locations. All meetings will be open to community participation and all minutes and resulting work is freely available under open sourceterms via the www.biopax.org website.