Generation of singlet oxygen mediated by silicon nanoassemblies for novel organic catalytic reactions

拟议的项目是在可持续化学技术领域，最终目的是发展一种清洁有机合成的新通用方法。将开发利用单线态氧在非映体和对映体选择反应中的反应活性的方法。该方法独特地基于最近发现的由硅纳米晶体组件介导的高效生成1O2与嵌入发光二极管的多功能结构反应器的新反应工程概念之间的协同作用。该提案确定了在清洁有机催化中采用过程强化新概念（通过非热活化和小型化，即增强质量和传热）和功能纳米材料的巨大潜力。最重要的是，该提案解决了清洁有机合成和分子非热活化领域的发展不足。

The proposed project is in the area of sustainable chemical technology and is ultimately aimed at developing a novel generic approach towards clean organic synthesis. The methodology, exploiting reactivity of singlet oxygen in diastereo- and enantioselective reactions, will be developed. The proposed methodology is, uniquely, based on the synergy between recently discovered highly effective generation of 1O2, mediated by silicon nanocrystals assemblies, and the novel reaction engineering concept of multifunctional structured reactors with imbedded light-emitting diodes. The proposal identifies the significant potential of adopting new concepts of process intensification (via non-thermal activation and miniaturisation, i.e. enhanced mass and heat transfer) and functional nanomaterials in clean organic catalysis. Most significantly, the proposal addresses the underdevelopments in the areas of clean organic synthesis and non-thermal activation of molecules.