Generation of singlet oxygen mediated by silicon nanoassemblies for novel organic catalytic reactions

拟议的项目属于可持续化学技术领域，最终目的是为清洁有机合成开发一种新的通用方法。将发展利用单线态氧在非对映和对映选择性反应中的反应性的方法学。所提出的方法独特地基于最近发现的由硅纳米晶组装介导的高效产生1O2的协同作用，以及具有嵌入发光二极管的多功能结构反应器的新的反应工程概念。该提案确定了在清洁有机催化中采用过程强化(通过非热活化和微型化，即强化质量和热量传递)和功能纳米材料的新概念的巨大潜力。最重要的是，该提案解决了清洁有机合成和分子的非热激活领域的不发达问题。

The proposed project is in the area of sustainable chemical technology and is ultimately aimed at developing a novel generic approach towards clean organic synthesis. The methodology, exploiting reactivity of singlet oxygen in diastereo- and enantioselective reactions, will be developed. The proposed methodology is, uniquely, based on the synergy between recently discovered highly effective generation of 1O2, mediated by silicon nanocrystals assemblies, and the novel reaction engineering concept of multifunctional structured reactors with imbedded light-emitting diodes. The proposal identifies the significant potential of adopting new concepts of process intensification (via non-thermal activation and miniaturisation, i.e. enhanced mass and heat transfer) and functional nanomaterials in clean organic catalysis. Most significantly, the proposal addresses the underdevelopments in the areas of clean organic synthesis and non-thermal activation of molecules.