Surveying & Assessing Firefighter Fitness & Electrocardiography: The SAFFE Study

描述（由申请人提供）：全国有超过一百万名消防员为地铁、农村社区和野生森林服务，公众取决于他们的最佳健康状态。然而，消防员死于心血管疾病的人数是警察的两倍，是急救人员的四倍。迄今为止，尽管消防员的心脏风险很高，而且具有重要的社会意义，但在消防活动中没有可用的生理记录，可以揭示消防员在执勤时死亡的原因。因此，调查和评估消防员健康和心电图：SAFFE研究的主要目的是开发一种无创风险分层方法，以更好地识别有心血管事件风险的消防员。在这项探索性/发展性研究中，将招募118名专业消防员参与研究方案，其中包括(1)基线心电图和V02测量，(2)梯度运动跑步机测试期间的最大容量心电图和V02测量，(3)值班心电图和VO2测量。连续12导联心电图将在轮班开始时开始，并在所有消防员活动期间保持24小时，包括：(1)火警呼叫，(2)医疗呼叫，(3)训练，(4)用餐，(5)运动和(6)休息/睡眠。在选定的时间段内，将在整个轮班期间获得间歇性V02措施，包括：火警呼叫、医疗呼叫和培训。表现出特定ECG异常和非线性HR/V02关系的消防员比例将在基线、最大容量和值班时报告。由于心脏事件是导致死亡的主要原因之一，使用生物测量（心电图和V02）来更好地识别为公众服务的高危急救人员，将有助于评估风险和评估优化健康的干预策略。全国有100多万名消防员为地铁、农村社区和野生森林服务，公众取决于他们的健康状况。然而，消防员死于心血管疾病的人数是警察的两倍，是急救人员的四倍。由于心脏事件是导致死亡的主要原因之一，使用生物测量（心电图和V02）来更好地识别为公众服务的高危急救人员，将有助于评估风险和评估优化健康的干预策略。

DESCRIPTION (provided by applicant): With over a million firefighters in the country servicing metro, rural communities, and wildlife forestry, the public depends on their optimal state of health. However, firefighters have twice as many cardiovascular deaths compared to police officers and four times the proportion among emergency medical responders. To date, despite the high cardiac risk for firefighters and its societal importance, there are no available physiological recordings during firefighting activities that may reveal why firefighters are dying on duty. Thus, the primary aim of the Surveying & Assessing Firefighter Fitness & Electrocardiograms: The SAFFE Study is to develop a non-invasive risk stratification approach to better identify firefighters at risk for cardiovascular events. For this exploratory/developmental study, 118 professional firefighters will be recruited to participate in the research protocol which includes (1) baseline ECG & V02 measures, (2) maximum capacity ECG & V02 during a graded exercise treadmill test and (3) on-duty ECG & VO2 measures. Continuous 12 lead ECG will be initiated at the beginning of the shift and maintained for 24 hours during all firefighter activities including: (1) fire calls, (2) medical calls, (3) training, (4) meals, (5) exercise, and (6) rest/sleep. Intermittent V02 measures will be obtained throughout the shift during select periods including: fire calls, medical calls and training. The proportion of firefighters that demonstrate specific ECG abnormalities and nonlinear HR/V02 relationship will be reported at baseline, maximum capacity and on-duty. With cardiac events as one of the leading causes of death, the use of biological measures (ECGs & V02) to better identify at-risk first responders who service the public, would aid in assessing risk and evaluating intervention strategies that optimize health. PUBLIC HEALTH RELEVANCE With over a million firefighters in the country servicing metro, rural communities and wildlife forestry, the public depends on their state of health. However, firefighters have twice as many cardiovascular deaths compared to police officers and four times the proportion among emergency medical responders. With cardiac events as one of the leading causes of death, the use of biological measures (ECGs & V02) to better identify at-risk first responders who service the public, would aid in assessing risk and evaluating intervention strategies that optimize health.