Postgraduate Training in Pediatric Oncology

描述(由申请人提供)：科罗拉多大学健康科学中心(UCHSC)和丹佛儿童医院的儿科肿瘤学奖学金项目，具有30多年的杰出历史。1993年，大量新的资源专门用于这一计划的发展，导致建立了骨髓移植单位、神经肿瘤学服务和一个基础科学家核心小组。此外，扩大了奖学金计划，研究员有机会在UCHSC系统的任何实验室进行研究。该培训计划是在2000年用这笔T32赠款资助的，目前提交的是这一支持的竞争性续签。目前，24个培训学院代表了广泛的科学学科，包括细胞周期控制和信号、转录调控和剪接、病毒学和免疫学。这些不同的学科和方法通过使用分子方法来解决基本的生物学问题，并通过它们对肿瘤学研究中的问题的适用性来统一。由于具有广泛的临床经验，儿童医院良好的临床声誉，以及新的研究机会，自1993年以来，奖学金候选人在质量和对学术事业的奉献方面一直在不断提高。事实上，自1993年以来的19名毕业生中，有15人现在担任教职。最低奖学金期限为三年，第一年仅限临床培训。目前该计划有11名研究员，他们都以前完成了儿科住院医生的培训，其中8人目前正在接受超过他们第一个临床研究员年的研究培训。这项建议寻求为那些选择在奖学金的第二年和随后几年从事与儿科肿瘤学相关研究的研究员提供资金。因此，无论是历史还是最近的发展，都标志着这一培训计划是全国最好的培训计划之一。

DESCRIPTION (provided by applicant): The Pediatric Oncology Fellowship Program at the University of Colorado Health Sciences Center (UCHSC) and Denver Children's Hospital, has a distinguished history spanning over 30 years. In 1993, substantial new resources were dedicated to the development of this Program, leading to the establishment of a Bone Marrow Transplant unit, Neuro-oncology service, and a core group of basic scientists. In addition, the fellowship program was expanded and fellows were given the opportunity to perform research in any laboratory in the UCHSC system. The training program was funded in 2000 with this T32 grant, and the current submission is the competing renewal of this support. Presently 24 Training Faculty represent a broad range of scientific disciplines including cell cycle control and signaling, transcriptional regulation and splicing, virology, and immunology. These diverse disciplines and approaches are unified by use of molecular approaches to address fundamental biological questions, and by their applicability to problems in oncology research. Because of the breadth of the clinical experience, the fine clinical reputation of the Children's Hospital, and the new research opportunities available, fellowship candidates since 1993 have consistently increased in quality and dedication to an academic career. Indeed, 15 of 19 graduates since 1993 are now in academic faculty positions. The minimal fellowship duration is three years, with the first year exclusively clinical training. Currently there are 11 fellows in the Program, all of whom have previously completed their Pediatric residencies, with 8 currently in research training beyond their first clinical fellowship year. This proposal seeks funding for those fellows who elect to pursue research related to Pediatric Oncology in the second and subsequent years of the fellowship. Both history and recent developments thus mark this training program as one of the best in the nation.