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中文摘要
翻译
化学和产品开发核心的目标是提供足够数量的 应向每个核心和项目调查候选杀微生物剂,以确保总目标 方案得到了有效的满足。此外,ImQuest制药公司作为该项目的企业合作伙伴, 将通过正在进行的研究提供所需的协助,以确保产品开发计划 利用该联盟将生产的尖端科学方法和技术来满足这些要求。 ImQuest制药公司之间将有保密协议和谅解备忘录 为公司及所有团队成员和机构顺利完成研究目标提供便利 以及开始对相互独立的单一和组合产品进行IND指导的研究 以及阴道和直肠使用的长效杀微生物剂替代品。ImQuest制药公司将提供 IND指导的科学和监管能力,通过自己的资源或 通过与美国国立卫生研究院和其他基金会的关系或讨论 杀微生物剂伙伴关系(IPM)。
英文摘要
The objectives of the Chemistry and Product Development Core are to provide sufficient quantities of the candidate microbicides to be investigated to each Core and Project to assure that the goals of the total Program are met efficiently. In addition, ImQuest Pharmaceuticals, as the Corporate Partner of the project, will provide needed assistance with studies being performed to assure that product development initiatives are met utilizing the cutting edge scientific methods and technology that will be produced by the consortium. ImQuest Pharmaceuticals will have confidentiality agreements and Memorandum of Understanding between the company and all team members and Institutions to facilitate successful completion of the research goals and the initiation of IND-directed studies on single and combination products which are coitally independent and long lasting microbicide alternatives for vaginal and rectal use. ImQuest Pharmaceuticals will provide IND-directed scientific and regulatory capacity to develop these products through their own resources or through emerging relationships or discussions with the NIH and other Foundations such as International Partnership for Microbicides (IPM).
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Critical Path IND-enabling Studies, Regulatory, and Product Development
  • 批准号:
    8405106
  • 项目类别:
  • 资助金额:
    $94.2万
  • 财政年份:
    2012
  • 负责人:
    Robert Walter Buckheit
  • 依托单位:
Determination of Dosing Concentrations of Formulated APIs using the MTSA
  • 批准号:
    8404125
  • 项目类别:
  • 资助金额:
    $33.75万
  • 财政年份:
    2012
  • 负责人:
    Robert Walter Buckheit
  • 依托单位:
Development and Evaluation of Dual Compartment Combination Microbicides
  • 批准号:
    8699496
  • 项目类别:
  • 资助金额:
    $287.64万
  • 财政年份:
    2012
  • 负责人:
    Robert Walter Buckheit
  • 依托单位:
Development and Evaluation of Dual Compartment Combination Microbicides
  • 批准号:
    8862358
  • 项目类别:
  • 资助金额:
    $244.32万
  • 财政年份:
    2012
  • 负责人:
    Robert Walter Buckheit
  • 依托单位:
海外基金