Hype or Hope? platelet-Rich plasma as a symptom- and disEaSe-modifying Treatment fOR knee ostEoarthritis - the RESTORE trial

膝骨性关节炎(OA)是一个世界性的重大公共卫生问题，没有治愈的方法。因此，需要安全有效的治疗方法来减轻症状，减缓结构性疾病的进展。这项临床试验旨在测试膝关节内注射富含血小板血浆(一种血液产品)对288名膝骨性关节炎患者的疼痛和关节结构的影响。这一结果将为确定是否应该使用富血小板血浆治疗膝骨性关节炎提供高质量的证据。

Knee osteoarthritis (OA) is a major public health problem worldwide with no cure. Thus safe and effective treatments that reduce symptoms and slow structural disease progression are needed. This clinical trial aims to test the effects of injections of platelet-rich plasma (a blood product) into the knee on pain and joint structure in 288 people with knee OA. The results will provide high quality evidence to determine whether platelet rich plasma should be used to treat knee OA.