CSORDA Mouse Core (CMC)

主要研究者/项目负责人：Evans，Christopher J.，哲学博士、CSORDA小鼠核心 CORE：CSORDA小鼠核心 摘要： CSORDA小鼠核心（CMC）将协调和监督所有项目的动物需求。 中心在UCLA进行。它将维持中心所需的所有突变动物品系， 向所有中心研究部门提供这些动物的可靠供应。CMC还将 基因型突变动物用于育种和研究中心。的所有项目 CSORDA将广泛使用小鼠，特别是那些来自转基因品系的小鼠。 CSORDA小鼠核心（CMC）的目的是为所有研究人员提供这些研究对象。 中心的组成部分。CMC将建立和维持基因操作小鼠的品系 使用的 件. CMC是在上一个调查周期中成立的，并制定了一套坚实的 标准化程序来实现这一目标。CMC不断与所有组件协商 在该中心，需要哪些特定品系的小鼠，以及满足要求所需的数量。 在这些组件中进行拟议实验的要求。

Principal Investigator/Program Director: Evans, Christopher J., Ph.D., CSORDA Mouse Core CORE: CSORDA Mouse Core ABSTRACT: The CSORDA Mouse Core (CMC) will coordinate and oversee the animal needs of all projects in the Center conducted at UCLA. It will maintain all mutant animal lines needed by the center and make a reliable supply of these animals available to all Center research components. The CMC will also genotype mutant animals used in by the Center for breeding and research. All the Projects of CSORDA will make extensive use of mice, particularly those coming from genetically modified lines. The purpose of the CSORDA Mouse Core (CMC) is to provide these research subjects to all the Components of the Center. The CMC will establish and maintain lines of genetically manipulated mice for use by the Components. The CMC was established in the previous finding cycle and developed a solid set of standardized procedures to accomplish this goal. The CMC continually consults with all Components in the Center about which particular strains of mice are needed and the numbers required to meet the demands of proposed experiments within those Components.