Colorado Career Development Program in the Genetics and Genomics of Lung Diseases

描述(由申请人提供)： 鉴于遗传学和基因组学技术在人类疾病中的应用日益重要，并意识到肺部疾病研究可以从这些技术的广泛使用中获益的程度，我们提出了科罗拉多州肺遗传学和基因组学计划(CPGGP)，以促进肺遗传学和基因组学研究学者的职业发展。拟议的职业发展计划的目标：培养肺部疾病遗传学和基因组学临床研究领域的领导者建立一个课程，结合我们现有的肺部医学培训、人类医学遗传学和临床科学计划加强合作，招募来自不同背景的优秀学者我们建议的计划响应NHLBI蓝图，并包括以下组成部分以实现这些目标：旨在使所有学者对肺部疾病遗传学和基因组学研究的基础和现实有相应了解的课程，无论他们在四种主要肺部疾病：急性肺损伤/急性呼吸窘迫综合征(ALI/ARDS)、肺高血压(PH)、慢性阻塞性肺疾病/癌症预防(COPD/CA)和肉芽肿性肺疾病(GDPS)中通过正在进行的遗传学和/或基因组学研究的研究机会进行研究的背景广度如何，通过共同指导的研究项目为独立临床研究做准备，通过临床研究设计、监管监督、拨款撰写、人类受试者使用和人类医学遗传学研究计划评估和培训中固有的伦理道德，该计划吸收了肺部疾病、医学遗传学、生物信息学、以及临床科学培训计划，以便为学者提供机会，就他们通过该计划的旅程做出重大选择，并优化他们未来的成功。在目前的模式下，不仅学者将受益，导师也将从他们参与该计划中受益。通过更广泛地涵盖选定的肺部疾病，该计划可以对遗传学和基因组学在肺部疾病中的应用产生显著影响。 (摘要结束)

DESCRIPTION (provided by applicant): In recognition of the growing importance of genetics and genomics techniques applied to human disease, and in awareness of the extent to which lung disease research could benefit from expanded use of these technologies, we propose the Colorado Pulmonary Genetics and Genomics Program (CPGGP) for the career development of scholars in pulmonary genetics and genomics research. Objectives of the proposed career development program: Train leaders in the field of clinical research in lung disease genetics and genomics Build a curriculum combining the best of our existing pulmonary medicine training, human medical genetics, and clinical sciences programs Increase collaboration Recruit excellent scholars from various backgrounds Our proposed program responds to the NHLBI blueprint and has the following components for achieving these objectives: A curriculum designed to bring all scholars to a commensurate understanding of the fundamentals and realities of lung disease genetics and genomics research, regardless of their background Breadth of study through research opportunities in ongoing genetics and/or genomics research in one of four major lung diseases: Acute Lung Injury / Acute Respiratory Distress Syndrome (ALI/ARDS), Pulmonary Hypertension (PH), Chronic Obstructive Pulmonary Disease / Cancer Prevention (COPD/CA), and Granulomatous Lung Disease Collaboration through co-mentored research projects Preparation for independent clinical research through training in clinical research design, regulatory oversight, grant writing, human subject use, and ethics inherent in human medical genetics research Program evaluation and trainee follow-up The Program assimilates the expertise resident in Pulmonary Diseases, Medical Genetics, Bioinformatics, and the Clinical Sciences Training Program in order to afford Scholars the opportunity for significant choices regarding their journey through the Program, and optimizing their future success. In the current paradigm, not only will Scholars benefit, but Mentors will also profit through their involvement in the Program. By more broadly covering selected Pulmonary Diseases, the Program can have a pronounced impact on the application of genetics and genomics to lung diseases. (End of Abstract)