IMAGING, DATA ANALYSIS AND ACUISITION MODULE

概述 成像、数据分析和采集模块（称为“成像模块”）的总体目的是 模块”）是双重的。首先，它将为最先进的静态和动态成像提供设施和支持 来自人类和非人类视觉系统的各种区域的固定和活组织。二是会 有利于开发先进和高度专业化的数据采集和分析软件。与 成像到数字方法的完全转换，复杂的数据采集和分析技术， 需要定量地检查视觉系统的结构，发展和功能。该模块提供 用于图像采集的通用硬件，以及数据采集和 分析. 在过去的十年里，数字成像技术及其在基础医学中的应用发生了革命性的变化。 生物医学研究成像模块是将这项技术带入视觉的关键资源 耶鲁的社区先进的成像设备是昂贵的，并且通常无法购买， 由一名调查员的资源维持。愿景核心计划的存在，以及 成像模块在耶鲁大学已作为杠杆的发展和收购显微镜和相关的 设备使用耶鲁大学的资源，辅以愿景计划的资金。这使得耶鲁 视觉研究人员采用新的工具和方法来发现视觉科学。在上一个资助期内， 成像模块以多种方式扩展。首先，我们的奥林巴斯倒置共聚焦显微镜是显着 升级其次，我们为标准立柱采购了SPOT数码相机和相关SPOT软件 （Zeiss Axiovert）和倒置（Zeiss Axioskop）显微镜。这些改进简化了图像 为视觉研究人员提供采集和分析，而不影响质量，从而显著拓宽 耶鲁大学视觉科学研究人员中的用户群使用这些核心设施。

Overview The overall purpose of the Imaging, Data Analysis and Acquisition Module (referred to as the 'Imaging Module') is two-fold. First, it will provide facilities and support for state-of-the art static and dynamic imaging of fixed and living tissue from a variety of regions of the human and non-human visual system. Second, it will facilitate the development of advanced and highly specialized data acquisition and analysis software. With the complete conversion of imaging to digital methods, sophisticated data acquisition and analysis techniques are required to quantitatively examine visual system structure, development and function. This module supplies common hardware for image acquisition, as well as software development and support for data acquisition and analysis. Over the past decade there has been a revolution in digital imaging technology and its application to basic biomedical research. The Imaging Module has been a critical resource in bringing this technology to the vision community at Yale. Advanced imaging equipment is expensive and typically cannot be purchased and maintained with the resources of a single investigator. The existence of the Vision Core Program and this Imaging Module at Yale has served as leverage for the development and acquisition of microscopes and related equipment using Yale University resources supplemented by Vision Program funds. This has enabled Yale vision researchers to adopt new tools and approaches to vision science discoveries. In the last grant period, our Imaging Module expanded in several ways. First, our Olympus inverted confocal microscope was significantly upgraded. Second, we acquired SPOT digital cameras and associated SPOT software for our standard upright (Zeiss Axiovert) and inverted (Zeiss Axioskop) microscopes. These improvements have simplified image acquisition and analysis for vision researchers without compromising quality, thereby significantly broadening the user base among vision science researchers at Yale for these core facilities.