Pediatric Quality of Life: Is it lost in traduccion?

描述（由申请人提供）：哮喘是影响儿童最常见的慢性疾病。有人建议，为了全面了解哮喘对儿童的影响，有必要直接测量生活质量（QOL） （Juniper et al., 1996）。一个有效的概念模型来衡量哮喘儿童的生活质量，将有助于提供者了解对患者生活影响最大的条件，并有助于评估不同患者护理方法的相对重要性（Wilson & Cleary, 1997）。Juniper及其同事（1996）开发了一种测量哮喘儿童生活质量的概念模型，即儿童哮喘生活质量问卷（PAQLQ）。这份问卷是在一个种族相同的样本中开发的，然后被翻译成包括西班牙语在内的20多种语言。首席研究员打算使用PAQLQ作为分组比较的结果测量，讲英语的孩子和讲西班牙语的孩子。然而，对于人群组间比较PAQLQ的测量不变性了解甚少。相对较新的分析技术可用于评估测量不变性的工具，这是适当的人口群体之间比较的必要要求。Stewart和Napoles-施普林格（2000）指出，像PAQLQ这样的自我报告测量的有效比较要求这些概念在不同群体中具有相似的含义。度量必须以类似的方式在被比较的组之间符合度量不变性。因此，本研究的目的是利用二手数据，利用扫描电镜和测量不变性分析来检验PAQLQ的英语和西班牙语版本的概念和测量特性。测量不变性分析包括在两个或多个独立的人群中测试被测构念的等效性，以确保每个群体的心理测量特性相似，因此群体比较是合适的。以下是这个应用程序的目标：利用扫描电镜的验证性方法，对英语和西班牙语版本的PAQLQ的结构效度进行评估。目标2。使用度量不变性分析评估PAQLQ的英语和西班牙语版本的等价性。目标3：如果PAQLQ的英语和西班牙语版本之间没有达到测量不变性，那么将采取几个步骤，使用SEM来改进工具，以提高其结构效度，跨人群的测量等效性，并尽量减少组间分析的偏差。当使用生活质量作为结果来捕捉不同群体之间的优质护理时，至关重要的是研究人员和决策者对该工具的保真度有信心。儿童哮喘生活质量问卷尚未进行测量不变性测试，这是一种相对较新的分析技术，是进行适当的组间比较的必要条件

DESCRIPTION (provided by applicant): Asthma is the most common chronic disease affecting children. It has been suggested that to gain a full picture of the impact of asthma on children, it is necessary to make direct measurements of quality of life (QOL) (Juniper et al., 1996). A valid conceptual model to measure QOL in children living with asthma would help providers learn about conditions that have the greatest impact on patients' lives and help evaluate the relative importance of different approaches to patient care (Wilson & Cleary, 1997). Juniper and colleagues (1996) developed a conceptual model to measure QOL of children living with asthma, the Pediatric Asthma Quality of Life Questionnaire (PAQLQ). This questionnaire was developed within an ethnically homogenous sample and then translated into over 20 languages including Spanish. The Principal Investigator intends on using the PAQLQ as an outcome measure for group comparisons, English-speaking versus Spanish-speaking children. However, little is know about the measurement invariance of the PAQLQ for between population group comparisons. Relatively new analytical techniques are available to evaluate instruments for measurement invariance which is a necessary requirement for appropriate between population group comparisons. Stewart and Napoles- Springer (2000) stated that a valid comparison of self-reported measures like the PAQLQ requires that the concepts have similar meaning across groups. Measures must conform to measurement invariance in similar ways across the groups being compared. Thus the purpose of the proposed research is, using secondary data, to examine the concepts and measurement properties of the English- and Spanish-language versions of the PAQLQ using SEM and measurement invariance analysis. Measurement invariance analysis involves testing the equivalence of measured constructs in two or more independent population groups to assure that the psychometric properties are similar in each group and therefore group comparisons are appropriate. The following are the aims for this application: Aim 1. Using the confirmatory approaches of SEM evaluate the construct validity of the PAQLQ in both the English- and Spanish-language versions. Aim 2. Evaluate the equivalence of the English- and Spanish-language versions of the PAQLQ using measurement invariance analysis. Aim 3 if measurement invariance is not achieved between the English- and Spanish-language versions of the PAQLQ, then several steps will be taken using SEM to refine the instrument to improve its construct validity, measurement equivalence across populations, and to minimize bias fro between group analyses. When using quality of life as an outcome to capture quality care, between diverse groups, it is vital that researchers and policy makers have confidence in the fidelity of the instrument. The Pediatric Asthma Quality of Life Questionnaire has not been tested for measurement invariance, a relatively new analytical technique, which is a necessary requirement for appropriate between group comparisons