Eleventh Meeting of the Society for Research on Biological Rhythms

描述(申请人提供)：本提案请求对生物节律研究学会第11次会议提供部分支持。这次会议将于2008年5月17日至22日在佛罗里达州的德斯汀举行。这次会议主要致力于研究生物钟。这些时钟被认为是不同生理过程的适当计时的基础。近年来，人们越来越认识到，紊乱的节律可能是多种人类疾病的基础或促成因素。此外，我们对核心计时机制的理解也发生了一场分子革命。总而言之，这些发现为理解各种疾病的分子基础提供了基础。这次会议的主要目的是：1)建立一个在昼夜节律生物学领域所有主要方面进行尖端工作的顶尖科学家的计划；2)促进跨学科科学家之间的新的合作互动；3)突出时间生物学研究的比较方法，重点是与人类生理学和疾病的比较；以及4)促进年轻、代表性不足的群体和残疾人的参与。这次会议将汇集来自广泛国际人才库的500多名科学家。会议将分为15场座谈会、6场幻灯片、2场海报、1场专题讲座和1场总统专题讨论会。已确定的专题讨论会和初步发言者名单包括青年和知名科学家、女科学家以及使用各种研究模式的各国科学家。已经作出了努力，包括来自田间以外的人，以增加交叉受精的可能性。为了进一步促进讨论和合作，下午安排了充足的自由时间来鼓励互动。此外，会场的“自给自足”性质也支持了这一目标。鉴于生物钟在各种生理系统中的作用，这次会议应该会促进我们对各种人类疾病的理解，最明显的是在睡眠障碍等神经疾病和精神健康方面。公共卫生相关性：生物钟越来越被认为是人类健康和疾病的重要贡献者。在生物节律研究学会第11次会议上提出的这项研究调查了这些联系，并最终可能导致更好的诊断和治疗。

DESCRIPTION (provided by applicant): This proposal requests partial support for the 11th Meeting of the Society for Research on Biological Rhythms. This meeting will occur in Destin, Florida from May 17-22, 2008. The meeting is largely devoted to the study of circadian clocks. These clocks are thought to underlie the appropriate timing of diverse physiological processes. In recent years, there is an increasing recognition that disordered rhythms may underlie or contribute to a variety of human diseases. In addition, there has been a molecular revolution in our understanding of core timing mechanisms. Together, these discoveries provide the basis for understanding the molecular basis of a variety of diseases. The major aims of this conference are to: 1) put together a program of top-notch scientists doing cutting-edge work in all major aspects of the field of circadian biology, 2) promote new collaborative interactions between scientists across disciplines, 3) highlight comparative approaches to studies in chronobiology with an emphasis on comparison to human physiology and disease, and 4) promote the participation of young, underrepresented groups, and persons with disabilities. The conference will assemble over 500 scientists from a broad international pool. The meeting will be organized into 15 symposia, 6 slide sessions, two poster sessions, one special lecture and one special Presidential symposia. The established symposia and preliminary list of speakers encompass both young and established scientists, women scientists and those from a variety of countries using a variety of research models. Efforts have been made it include those from outside the field to increase the potential for cross- fertilization. To further promote discussion and collaborations, ample free time has been scheduled during the afternoons to encourage interactions. In addition, the "self-contained" nature of the conference site also supports this goal. Given the role of circadian clocks in a variety of physiological systems, the conference should promote our understanding of a variety of human diseases, most notably in neurological disorders such as sleep disorders, and mental health. PUBLIC HEALTH RELEVANCE: Circadian clocks are increasingly appreciated as important contributors to human health and disease. The research presented at the 11th meeting of the Society for Research on Biological Rhythms investigates these links, and could ultimately lead to better diagnostics and therapeutics.