The University of Rochester's Clinical and Translational Science Institute

罗切斯特大学临床和转化科学研究所(UR CTSI)将被创建为 临床和转化科学的学术之家，提供集中、集成的基础设施。 在UR CTSI项目主任拥有空间、教职员工、 预算和与CTSI有关的其他资源，其中GCRC当前预算的大部分是 分布到CTSI的关键功能支持这些功能，我们计划将这两个截然不同的功能 将临床和转化科学的研究领域整合为一门新学科。这门学科的目标是 包括创造诊断、预防和治疗人类疾病的新知识和新技术，以及 他建立了一个环境，催化他们在社区的临床实践中的应用。至 为了实现这些目标，我们提出了具体目标，涉及：新颖的方法；试点研究；升级 生物医学信息学、流行病学、研究设计、伦理和监管支持；社区 参与；新技术和新资源；新的教育和培训计划；最新消息 约克集团；以及对业绩成果的严格评价和衡量。战略规划 对于UR CTSI，在本RFA之前已经进行了几年。机构支持的证据 包括承诺新建150,000平方米。英国《金融时报》临床和翻译科学大楼(CTSB) 指导临床和翻译研究的教师将与学生和实习生一起参加 现有的和新的学位授予计划，具有辅助的监管和行政职能，以及 在生物统计学、流行病学和生物医学等合作学科中工作 信息学。UR CTSI的主任和联席主任将整合临床和翻译科学 CTSB中包含的功能与位于其他校园位置的功能，如功能 基因组学、其他翻译资源和综合临床研究中心(GCRC)。作为一个整体 作为CTSI的一部分，GCRC将搬进一个新装修的10,500平方英尺的设施，在街对面 CTSB，具有增强的功能和主体访问权限。此外，城市交通安全倡议还将产生双向协同效应 与当地社区团体(学校系统、信仰社区、商业、基金会)和其他北部地区 纽约的机构。此外，UR CTSI将实现跨学科和跨领域的数据共享 机构，同时确保人类主体的隐私和机密性。总而言之，通过合并和 将新设施与增强的基础设施、社区和州政府部门集成在一起， 现有研究和培训的基础，以及从根本上重组的行政结构， CTSI将改变UR的临床和翻译科学的开展，并在全国范围内为 锻造这一新学科。。

The University of Rochester Clinical and Translational Science Institute (UR CTSI) will be created as the academic home for clinical and translational science, providing a centralized, integrated infrastructure. Under a systemof governance in which the UR CTSI Program Director has authority over space, faculty, budgets, and other resources related to the CTSI, and in which much of the current GCRC budget is distributed to CTSI Key Functions in support of these functions, we plan to transformthe two distinct research fields of clinical and translational science into a single new discipline. The goals of this discipline nclude the creation of new knowledgeand techniques to diagnose, prevent and treat human disease, and he establishment of an environment that catalyzes their application to clinical practice in the community. To achieve these goals, we propose specific aims involving: novel methodologies; pilot studies; upgraded biomedical informatics, epidemiology, research design, ethics, and regulatory support; community engagement; new technology and resourcecores; new educational and training programs; an UpstateNew York Consortium; and rigorous evaluation and measurement of performanceoutcomes. Strategic planning for the UR CTSI has been underway for several years prior to this RFA. Evidence of institutional support includes commitment to a new 150,000 sq. ft. Clinical and Translational Science Building (CTSB) in which faculty conducting clinical and translational researchwill be brought together with students and trainees in existing and new degree-granting programs,with supporting regulatory and administrative functions, and with facultyworking in collaborative disciplines such as biostatistics, epidemiology, and biomedical nformatics. The Director and Co-Directors of the UR CTSI will integrate the clinical and translationalscience functions contained in the CTSB with those functions located at other campus locations, such as functional genomics, other translational resources, and the General Clinical Research Center (GCRC). As an integral part of the CTSI, the GCRCwill move into a newly-renovated 10,500 sq ft facility across the street from the CTSB, with enhanced functionality and subject access. As well, the URCTSI will create two-way synergies with local community groups (school system, faith community, business, foundations) and with other Upstate New York institutions. Further, the UR CTSI will enable the sharing of data across disciplines andacross institutions while assuring the privacy and confidentiality of human subjects. In summary, by coalescing and integrating new facilities with enhanced infrastructure, community and state-widepartnerships, astrong foundation of existing research and training, and a fundamentally reorganizedadministrative structure, the CTSI will transform the conduct of clinical and translational science at UR and contribute nationally to the forging of this new discipline. .