ANALYSIS OF BEATING HEART INTRACARDIAC SURGERY

这个子项目是许多利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本项目的目标是通过机器人器械控制和软组织力学开发入路器械、成像技术和安全措施，以实现心脏跳动心内外科手术。具体而言，在软组织力学领域，我们的目标是表征正常和患病心房的机械特性，以更好地了解这些组织对跳动心脏内经心房手术的耐受性。 McCulloch教授开发的猪心房解剖数据库将作为我们在宏观和微观解剖特征方面表征心房的基础。此外，他的团队开发的连续性建模软件以及使用该工具提供的支持将使我们能够开发该模型并验证我们对软组织特性的物理测量。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The goals of this project are to develop access devices, imaging techniques and safety measures through robotic instrument control and soft tissue mechanics to enable beating heart intracardiac surgical procedures. Specifically, in the area of soft tissue mechanics, we aim to characterize the mechanical properties of both normal and diseased atria to better understand the tolerance of these tissues to trans-atrial surgery inside a beating heart. The database of porcine atrial anatomy developed by Prof. McCulloch will serve as a basis for our characterization of the atria in terms of both macroscopic and microscopic anatomic features. Furthermore, the Continuity modeling software developed by his group and the support afforded in the use of this tool will allow us to develop this model and validate our physical measurements of the soft tissue properties.