STRUCTURAL STUDIES OF PROTEINS FROM HYPERTHERMOHILIC VIRUSES

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 NE-CAT光束线的工作重点是确定STIV病毒蛋白B129的结构。这种蛋白质的功能不能通过使用BLAST搜索的序列相似性来确定，也不能通过CD搜索或线索来确定。然而，我们预计蛋白质的结构将允许我们识别结构同源物，从而形成关于其功能的可测试假说。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Work at the NE-CAT beamline was focused on determining the structure of the STIV viral protein B129. The function of this protein can not be determined by sequence similarity using BLAST searches, or by CD searches or threading. We anticipate, however, that the structure of the protein will allow us to identify structural homologs, and thus to formulate a testable hypothesis regarding its function.