PHENOTYPING SCIENCE

表型科学为癌症中心的教职员工提供了各种工具、技术和专业知识 进行基因表达、分子生物学、流式细胞术和蛋白质化学方法。创建为 由于2004年科学服务部门的重组，该部门由前者组成 微量化学和流式细胞术服务。微量化学已经得到了癌症中心的支持 自17年前发展这项服务以来的支持补助金，同时支持流式细胞术 在整个23年的赠款期限内。表型科学服务为研究人员提供了 到最先进的基因表达技术、核酸分离和质量评估、基因 靶向和转基因构建设计、蛋白质化学服务、先进的流式细胞仪技术 和一种单抗来源。获得这些服务对癌症中心的工作人员来说是必不可少的。总括 表型科学服务的使用在过去五年中增加了55%。表型分析 科学项目负责人，高级职员科学家德里·鲁布皮安博士负责监督这项服务费 手术。三名基因表达技术专家，两名流式细胞仪专家，三名分子生物学家，一种蛋白质 化学家和高级经理在研究所占地1,851平方英尺的实验室设施工作 实验室4单元大楼。该服务是动态的，不断增加和改进其阵列 满足癌症中心会员需求的服务。自上次续签以来，意义重大 技术的进步为多色流的扩展和改进提供了条件 细胞学和分选、基因表达微阵列分析和多重蛋白质分析服务。 表型鉴定科学与该中心的其他服务完全整合，包括 计算科学、生殖科学-细胞生物学和显微注射，以及SNP基因分型 为癌症研究提供一整套支持服务。鲁普尼安博士与 癌症中心用户、服务人员和中心管理人员确保研究需求在 最高效、最具成本效益和技术上最先进的方式。

Phenotyping Sciences provides Cancer Center faculty with diverse tools, techniques and expertise for the conduct of gene expression, molecular biology, flow cytometry, and protein chemistry methods. Created as a result of the reorganization of Scientific Services in 2004, this department comprises the former Microchemistry and Flow Cytometry Services. Microchemistry has been supported by the Cancer Center Support Grant since the Service was developed 17 years ago, while Flow Cytometry has been supported for the full 23-year term of the grant. The Phenotyping Sciences Service provides researchers with access to state-of-the-art gene expression technologies, nucleic acid isolation and quality assessment, gene targeting and transgenic construct design, protein chemistry services, advanced flow cytometric technology and a monoclonal antibody resource. Access to these services is essential to Cancer Center staff. Overall use of the Phenotyping Sciences Service has increased by 55% over the past five years. The Phenotyping Sciences Project Leader, Senior Staff Scientist Dr. Derry Roopenian, oversees this fee-for-service operation. Three gene expression technologists, two flow cytometrists, three molecular biologists, a protein chemist, and senior manager staff the facility which occupies 1,851 ft2 of laboratory space in the Research Laboratory Unit 4 building. The Service is dynamic, continuously increasing and improving its array of services to meet the needs of the Cancer Center members. Since the last renewal, significant advancements in technology have provided for the expansion and improvement of multi-color flow cytometry and sorting, gene expression microarray analysis, and multiplexed protein assay services. Phenotyping Sciences is completely integrated with the other services at the Center, including Computational Sciences, Reproductive Sciences-Cell Biology and Microinjection, and SNP Genotyping to provide a comprehensive set of support services for cancer research. Dr. Roopenian communicates with the Cancer Center users, Service staff and Center Administration to ensure that research needs are met in the most efficient, cost-effective and technically current manner.