Cancer Control Research Training Summer Institute

描述(申请人提供)：危地马拉正在经历流行病学转型，今天面临着重大传染病和非传染性疾病的“双重负担”疾病问题。然而，非传染性疾病的流行和死亡率受到不可靠、过时的国家数据收集系统的限制；危地马拉56.2%的人口生活在贫困中，是拉丁美洲贫困程度最高的国家之一，危地马拉的基础设施使疾病监测和研究成为一项挑战。国家癌症研究所(国家癌症研究所，INCAN)是危地马拉癌症数据的主要来源。在男性(皮肤癌、胃癌、前列腺癌和结肠癌)和女性(宫颈癌、乳腺癌、皮肤癌和胃癌)中，排名前十的癌症中有四种可以通过风险因素修改或筛查等干预措施来减少。然而，印加(和危地马拉大部分地区)的癌症干预研究和开发几乎是不存在的。迫切需要培训未来的临床医生和公共卫生工作者，使他们掌握人体研究、流行病学和文化与卫生相互作用的基本原理，重点是使合理的研究方法适应资源匮乏地区的限制。拟议的培训计划的长期目标是加强华盛顿大学解决国际癌症控制问题的机构能力，并通过开发可持续的癌症研究培训计划来加强INCAN的研究能力。拟议的计划将促进华盛顿大学不同教职员工与印加教职员工和实习生之间的指导关系和合作，并为未来的资源和资金来源创造机会。该项目的具体目标是：1.为危地马拉未来的研究人员开发一个癌症研究培训课程。2.指导和协助印度癌症研究所和华盛顿大学博士后实习生制定跨学科、跨机构的癌症研究方案。 公共卫生相关性：该培训计划意义重大，因为它满足了危地马拉对结构化研究方案的迫切需求，以有效地研究该国不断变化的疾病趋势，特别是癌症。它的创新之处在于，它将为一个资源贫乏的国家的未来研究人员开展可持续的培训。它将在华盛顿大学和印加大学之间发展持久的多学科合作关系，这将导致与癌症控制研究相关的政策的设计和实施。

DESCRIPTION (provided by applicant): Guatemala is undergoing an epidemiological transition and today faces the "double-burden" disease problem of significant Infectious and non-Infectious disease. However, prevalence and mortality rates of non- Infectious disease are limited by an unreliable, outdated national data collection system; with 56.2% of the population living In poverty and one of the highest poverty levels In Latin America, Guatemala's Infrastructure makes disease surveillance and research a challenge. The Institute Nacional de Cancerologia (National Cancer Institute, INCAN) Is the primary source for cancer data In Guatemala. Four of the top ten cancers in men (skin, stomach, prostate, and colon) and women (cervix, breast, skin, and stomach) could be decreased with Interventions such as risk factor modification or screening. However, cancer research and development of Interventions at INCAN (and most of Guatemala) has been practically non-existent. There Is an Immediate need to train future clinicians and public health workers in the fundamentals of human subjects research, epidemiology, and the interaction of culture and health, with a focus on adapting sound research methodologies to the constraints of a resource-challenged region. The long term goals of the proposed training program are to strengthen the institutional capacity at Washington University to address International cancer control and to strengthen INCAN's research capacity through the development of a sustainable cancer research training program. The proposed program will foster mentored relationships and collaborations between diverse faculty from Washington University and INCAN faculty and trainees, as well as create opportunities for future resources and sources of funding. The specific aims of this project are: 1. To develop a cancer research training course for future researchers in Guatemala. 2. To provide guidance to and assist with interdisciplinary, inter-institutional cancer research protocol development by INCAN and Washington University postdoctoral trainees. PUBLIC HEALTH RELEVANCE: The training program is significant because it addresses an immediate need in Guatemala for structured research protocols to effectively study the country's changing disease trends, particularly cancer. It is innovative in that it will develop sustainable training to future researchers in a resource-poor country. It will develop lasting multidisciplinary collaborative relationships between Washington University and INCAN that will lead to design and implementation of policy relevant to cancer control research.