Computational Resource and Dissemination Core

这个雄心勃勃的计划项目的总体科学目标是开发创新的统计方法， 癌症临床试验，可以帮助加速成功地将有效的新疗法引入实践 计算资源和传播核心（核心C）将执行几项关键职能， 实施和传播用于癌症设计和分析的统计方法 在五个研究项目中开发的临床试验。核心将负责开发，在密切 与项目调查人员合作，高效，健壮的代码实现统计方法，可以 用于评估广泛的模拟研究中的方法，并用于将方法应用于 核心B和其他来源汇编的数据。核心还将负责领导和促进， 与项目调查人员密切合作，开发强大、可靠、用户友好和记录良好的 适用于向参与设计的从业人员公开传播的软件应用程序 和癌症临床试验的分析。核心C将采用这些任务的最佳实践，并提供 推广这些应用程序所需的信息技术和教育基础设施。

The overall scientific goal of this ambitious Program Project is to develop innovative statistical methods for cancer clinical trials that can help to hasten successful introduction of effective new therapies into practice The Computational Resource and Dissemination Core (Core C) will carry out several critical functions related to the implementation and dissemination of the statistical methods for the design and analysis of cancer clinical trials developed in the five research projects. The Core will be tasked with developing, in close collaboration with project investigators, efficient, robust code implementing the statistical methods that can be used for evaluation of the methods in extensive simulation studies and for application of the methods to data compiled by Core B and from other sources. The Core will also be tasked with leading and facilitating, in close collaboration with project investigators, development of robust, reliable, user-friendly, and welldocumented software applications suitable for public dissemination to practitioners involved in the design and analysis of cancer clinical trials. Core C wili adopt best practices for these tasks and provide the necessary information technology and educational infrastructure to disseminate these applications.