David W. Smith Workshop on Malformations and Morphogenesis

描述(申请人提供)：在过去的29年里，大卫·W·史密斯关于畸形和形态发生的研讨会汇集了畸形学家、胚胎学家、解剖学家、遗传学家和其他致力于更好地理解人类畸形如何发生和形态发生的潜在机制的人。这些研讨会每年举行一次，是为了纪念大卫·W·史密斯博士的职业生涯，他是人类临床畸形学之父，首次发起了这些会议。研讨会为期约五天，通常在夏季的学术校园举行，有120至140人参加，他们是在提交摘要后挑选出来的，并由科学计划委员会审查。讲习班的目的是提供一种互动交流，因此仅限于提出该年情况的人。这些会议大约每五年在国际上举行一次，但大多数会议都在美国举行。组织者每年选择三到五个中心主题；这考虑到该主题上次成为焦点的时间、基于新的科学发展和新领域的及时性。这些会议包括研讨会形式，在这种形式下，对假设驱动的结论进行简短的陈述，然后进行激烈的讨论。这些会议有着广泛和激动人心的讨论历史，并为发展和招聘畸形和形态发生领域的研究员和初级教员提供了一个特别重要的重点。 公共卫生相关性：这份申请是为了继续为大卫·W·史密斯研讨会提供支持，为研究员、初级教员和选定数量的全体演讲者提供旅费。作为临床医生和基础科学家交流人类畸形发病机制信息的主要论坛，该研讨会已有一段历史。

DESCRIPTION (provided by applicant): For the past 29 years the David W. Smith Workshop on Malformations and Morphogenesis has brought together a mix of dysmorphologists, embryologists, anatomists, geneticists, and others who work on developing a better understanding of how human malformations occur and the underlying mechanisms of morphogenesis. The workshops are held annually and were initiated in celebration of the career of Dr. David W. Smith, who was the father of human clinical dysmorphology and first initiated these meetings. Workshops are held over approximately five days, typically on an academic campus in the summer, and have an attendance of 120 to 140 individuals who are selected following submissions of abstracts and reviewed by the scientific program committee. The workshop is intended to provide an interactive exchange and thus is limited only to those presenting that year. Approximately every five years the meetings have been held internationally, but most meetings took place in the United States. Each year three to five central topics are selected by the organizers; which takes into account when the topic had last been a focus, timeliness based on new scientific developments, and new fields. The meetings consist of a workshop format in which short presentations of hypothesis-driven findings are then followed by an intense discussion period. The meetings have a long history of wide-ranging and stimulating discussion, and have provided an especially important focus for the development and recruitment of fellows as well as junior faculty into the field of malformation and morphogenesis. PUBLIC HEALTH RELEVANCE: This application is a request to provide continuing support for the David W. Smith Workshop in the form of travel stipends for fellows, junior faculty, and a select number of plenary speakers. This Workshop has a history for being the primary forum where clinicians and basic scientists exchange information on the pathogenesis of human malformations.