National Career Development Program for Researchers in Pediatric Clinical Pharmacology

儿科临床药理学研究人员国家职业发展计划

• 批准号: 11001312
• 负责人: DANIEL K. BENJAMIN
• 金额: $ 29.41万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2024
• 资助国家: 美国
• 起止时间: 2024-01-23 至 2028-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/11001312
• 关键词: National; Career; Development; Program; Researchers

ABSTRACT The demand for pediatric clinical pharmacologists continues to grow, necessitating investment in career development programs to train the next generation of pediatric clinical pharmacologists. This new K12 application seeks to establish the “National Career Development Program for Researchers in Pediatric Clinical Pharmacology.” This program will combine faculty expertise, pediatric clinical pharmacology research programs, and clinical research resources from a nationally dispersed group of leading academic institutions. The goal for this national career development program is to enhance the existing training opportunities through the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Pediatric Clinical and Developmental Pharmacology Training Network (PCDPTN). Program faculty are grouped into three areas of subject matter expertise: 1) Pharmacokinetics/Pharmacodynamics and Clinical Trials, 2) Pharmacoepidemiology and Data Science, and 3) Translational Research. The program faculty are selected based on their outstanding research accomplishments and track record mentoring junior investigators. In addition, the proposed career development program will leverage resources provided by the Pediatric Trials Network (PTN), the Maternal and Pediatric Precision in Therapeutics (MPRINT) Hub, and other NICHD-sponsored programs. The participating institutions have outstanding research environments and a reputation for successful mentorship of junior faculty pursuing academic careers in pediatric clinical pharmacology. Each scholar will complete a research project within one of the theme areas for the career development program, and they will be matched with a primary research mentor and a faculty mentoring committee. Scholars will be able to leverage faculty expertise across the participating institutions for research and mentoring. In addition to the research project, scholars will complete professional development opportunities, including training and mentorship in pediatric clinical pharmacology, written and oral communication, methods for enhancing research reproducibility, and research ethics. An Internal Advisory Board comprised of experts in pediatric clinical pharmacology will help with scholar selection, developing strategic partnerships, and advising on program enhancements. In addition, an External Advisory Board composed of experts in pediatric and maternal pharmacology and with extensive experience mentoring junior faculty will meet annually with scholars and the Executive Committee and provide advice on the structure and future directions for the program. The program will be evaluated by the External Advisory Board and through scholar and mentor evaluations. This career development program will enable scholars to generate the publication record, preliminary data, and skill set that is necessary to be competitive for independent research grants. Following completion of the program, all scholars will be exceptionally well-positioned to pursue impactful careers focused on promoting the safe and effective use of medications in children.

摘要 对儿科临床药理学家的需求持续增长，需要对职业生涯进行投资 发展计划，以培养下一代儿科临床药理学家。新K12 申请旨在建立“国家儿科临床研究人员职业发展计划”， 药理学。”该计划将结合联合收割机教师的专业知识，儿科临床药理学研究计划， 和临床研究资源来自全国分散的领先学术机构。的目标 这个国家职业发展计划是为了通过尤尼斯提高现有的培训机会 Kennedy Shriver National Institute of Child Health and Human Development（NICHD）儿科临床和 发展药理学培训网络。课程教师分为三个领域， 主题专长：1）药代动力学/药效学和临床试验，2）药物流行病学 和数据科学，以及3）转化研究。该计划的教师是根据他们的杰出选择 研究成就和跟踪记录指导初级调查员。此外，建议的职业 开发计划将利用儿科试验网络（PTN）、孕产妇和 儿科精确治疗（MPRINT）中心和其他NICHD赞助的项目。与会 各院校拥有出色的研究环境，并以成功指导初级教师而闻名 从事儿科临床药理学的学术研究每个学者将完成一个研究项目 在职业发展计划的主题领域之一，他们将与一个主要的匹配， 研究导师和教师指导委员会。学者将能够利用教师的专业知识， 参与研究和指导的机构。除了研究项目，学者们还将完成 专业发展机会，包括儿科临床药理学的培训和指导， 书面和口头交流，提高研究再现性的方法，以及研究伦理。内部 由儿科临床药理学专家组成的咨询委员会将帮助选择学者， 发展战略合作伙伴关系，并就项目改进提供咨询。此外，外部咨询 委员会由儿科和孕产妇药理学专家组成，具有丰富的指导经验 初级教员将每年与学者和执行委员会举行会议，并就结构提供建议 以及该项目的未来方向。该计划将由外部咨询委员会评估，并通过 学者和导师评估。这一职业发展计划将使学者产生的 出版记录、初步数据和独立研究所需的竞争力 赠款。该计划完成后，所有学者将非常有利地追求有影响力的 职业侧重于促进儿童安全有效地使用药物。