Enhancement of Two Key Research Programs within the Sylvester Cancer Center

描述（由申请人提供）：Sylvester癌症中心（Sylvester）是一个会员制的矩阵组织，汇集了来自迈阿密大学两个不同学院18个不同部门的121名成员和133名附属教师调查人员，进行多学科癌症研究。跨学科的转化研究通过中心的七个多学科研究项目（mrp）得到促进。NCI目前为70个项目提供了192972.01亿美元的资金。Sylvester的病毒肿瘤学和生物行为肿瘤学mrp的持续发展是中心的最高优先事项之一。每个都通过利用教师优势的有凝聚力的研究主题来解决独特的社区需求。这两个都是相对较小的项目，它们已经确定了可以通过招聘来最好地填补的关键空白。我们推荐两名候选人，分别进入这两个项目。这份申请中提到的调查人员是根据去年秋天该中心的会员静修活动的战略规划确定的，当由于大学的财政挑战而暂停招聘时，他们已经对该中心进行了初步访问。幸运的是（对西尔维斯特来说）他们仍然有空，而且非常感兴趣。他们的研究发展的详细计划已经完成，评估总体成功的计划也已经完成。西尔维斯特的研究预算高度依赖于筹款、捐赠、机构支持和国家资助。所有这四个支持来源都受到了当前经济衰退的不利影响。该方案30的供资将为加强中心七个方案方案中的两个提供关键支持。作为一个区域资源，该中心对主要集水区有直接影响，包括居住在佛罗里达州东南部三个县125英里海岸线上的540万人。由于其以旅游为导向和以增长为基础的经济，该地区在当前的经济衰退中受到了特别严重的打击。西尔维斯特在医学院也有很强的互动性。所有教师的招聘都是与最合适的学术部门联合进行的。与其他中心和研究所的合作也很多，包括跨学科干细胞研究所、迈阿密人类基因组学研究所和迈阿密CTSA倡议。因此，加强这两个mrp将加强西尔维斯特和这个学术健康科学中心。

DESCRIPTION (Provided by the applicant): The Sylvester Cancer Center (Sylvester) is a membership-based, matrix organization which brings together 121 members and 133 affiliate faculty investigators from 18 different departments in two different schools of the University of Miami to conduct multidisciplinary cancer research. Interdisciplinary translational research is facilitated through the center's seven multidisciplinary research programs (MRPs). Total NCI funding is currently $19,297,201 million for 70 projects. Continuing development of Sylvester's Viral Oncology and Bio-behavioral Oncology MRPs are among the highest priorities of the Center. Each address unique community needs through cohesive research themes that take advantage of faculty strengths. Both are relatively small programs which have identified critical gaps that can be best filled through recruitment. We are proposing two candidates for recruitment - one into each of these Programs. The investigators named in this application were identified following strategic planning at the Center's membership retreat in the fall of last year, and had already made initial visits to the Center when recruiting was suspended due to financial challenges in the University. Fortunately (for Sylvester) they are still available and highly interested. Detailed plans for development of their research have been completed as has a plan for evaluation of overall success. The Sylvester research budget is highly dependent on fundraising, endowment, institutional support, and State funding. All four of these sources of support have been adversely impacted by the current recession. Funding of this P30 would provide critical support for strengthening two of the Center's seven MRPs. As a regional resource, the Center has a direct impact on a primary catchment area that includes 5.4 million people living along 125 miles of coastline in the three counties of southeast Florida. Because of its tourist oriented and growth based economy, this area has been particularly hard hit by the current recession. Sylvester is also highly interactive within the School of Medicine. All faculty recruitment is done jointly with the most appropriate academic department. Collaborations with other centers and institutes also abound, including the Interdisciplinary Stem Cell Institute, the Miami Institute for Human Genomics and the Miami CTSA initiative. It follows that enhancing these two MRPs will strengthen Sylvester and this Academic Health Science Center.