OBESITY INTERVENTION BIOMARKER FOLLOW-UP STUDY IN RURAL PENNSYLVANIA FAMILIES

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 肥胖症的流行需要发展具有创新性的合作性社区研究伙伴关系，这种伙伴关系可以促进改善公共健康的变化。 在与北方阿巴拉契亚癌症网络（NACN）和宾夕法尼亚州癌症研究所（PSCI）的合作中，我们正在为宾夕法尼亚州农村的低收入家庭制定一项干预措施。 这项干预研究目前由宾夕法尼亚州立大学外展健康主题倡议基金资助，作为一个试点项目，以评估干预后食物选择的变化，并在基线时收集血液样本。 我们的目标是试点测试的工具，程序和内容的干预设计为一个晚餐俱乐部，以促进家庭内的健康，通过培训和提供信息和食品配菜的食物厨师在家庭用餐服务。我们还将收集生物标本，以确定教育干预后血清瘦素是否增加或减少。 受试者：将包括20个家庭，每个家庭一名儿童/一名成人。参与者将是7至60岁，儿童和父母之一，自我报告身高，体重计算BMI在超重范围内的成年人（BMI = 25），都能够提供血液样本50毫升的成年人和不超过3毫升每公斤的儿童，成年女性参与者提供血液样本在同一时间在月经周期期间前后测量。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The epidemic of obesity calls for the development of collaborative community-research partnerships that are innovative and that can foster change that results in improved public health. In collaboration with the Northern Appalachia Cancer Network (NACN) and the Penn State Cancer Institute (PSCI), we are developing an intervention for low-income families of rural Pennsylvania. This intervention study is currently funded by the Penn State Outreach Health Thematic Initiative Fund as a pilot project to assess changes in food choices post intervention and to collect blood samples at baseline. Our objective is to pilot test the instruments, procedures, and content of an intervention designed as a supper club to promote wellness within the family through training and providing the food preparer with information and food side dishes to serve at family meals. We will also collect biologic specimens to determine whether serum leptin increases or decreases following the educational intervention. Subjects: will include 20 families, one child/one adult per family. Participate will be 7 to 60 years of age, child and one parent, self reported height, weight calculated BMI in the overweight range for the adult (BMI =25), both able to give a blood sample of 50 mls for adults and no more than 3 ml per kg for child, adult menstruating women participants to provide blood sample at the same time in the menstrual cycle during pre- and post-measurement.