METABOLIC CORRELATES OF FUNCTIONAL MRI

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 该项目的总体目标是开发和验证一种并发测量的方法 脑血流量(CBF)和葡萄糖代谢使用MRI和PET的多模式成像。 受试者在功能磁共振成像(FMRI)期间注入19F-脱氧葡萄糖(FDG)，以及 随后通过正电子发射计算机断层扫描测量功能磁共振期间的葡萄糖利用率。这项技术 将在研究CBF和健康代谢之间的耦合方面有各种应用 和疾病。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The overall goal of this project is to develop and validate a method for concurrent measurement of cerebral blood flow (CBF) and glucose metabolism using multimodal imaging with MRI and PET. Subjects are infused with 19F-fluorodeoxyglucose (FDG) during functional MRI (fMRI), and glucose utilization during the fMRI is subsequently measured with PET scanning. This technology will have a variety of applications in studying the coupling between CBF and metabolism in health and disease.