Development of Bioemulsifier Production to Advance Commercial Explotation Opportunities

这项提议旨在开发一套天然乳化剂(生物乳化剂)，这些乳化剂在医疗保健和食品饮料等行业中作为配料和生产加工剂显示出非凡的前景。乳化剂的使用很普遍，因为很多产品都需要混合“油和水”。生物乳化剂是微生物生产的表面活性分子，有望替代化学合成的品种，因为它们是天然的，具有潜在的低毒性和更好的功能性(例如起泡、稳定；耐极端温度和pH)。该项目旨在显著提高生物乳化剂的产量，以促进商业开发机会：(I)使用非转基因方法诱导和选择高产突变菌株；(Ii)优化微生物发酵；以及(Iii)改进回收和纯化工艺。通过市场研究，我们将确定商业化的市场机会和潜在障碍，发展和扩大与感兴趣的各方的现有合作，并探索这些生物乳化剂的商业用途。

This proposal aims to exploit a suite of natural emulsifiers (bioemulsifiers) that show exceptionalpromise as ingredients and production process agents in industries such as healthcare and food andbeverages. Emulsifier use is widespread because of the need to mix 'oil and water' in manyproducts. Bioemulsifiers are microbially produced surface-active molecules that are promisingalternatives to the chemically synthesised varieties because they are natural, have potentially lowertoxicities and improved functionality (e.g. foaming, stabilisation; tolerance to extremes oftemperature and pH). This project aims to significantly increase bioemulsifier production tofacilitate commercial exploitation opportunities, by: (i) induction and selection of hyper-producingmutant strains using non-GM methods; (ii) optimise microbial fermentation; and (iii) improverecovery and purification processes. Through market research we will identify market opportunitiesand potential barriers to commercialization and develop and extend existing collaborations withinterested parties and explore commercially uses for these bioemulsifiers.