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中文摘要
翻译
流式细胞仪共享资源(FCSR)提供最先进的分析和分类 以负担得起的成本向需要流动的加州大学洛杉矶分校调查人员提供仪器和尖端专业知识 来继续他们的研究。琼森综合癌症中心(JCCC)建立了这个 1988年在全校范围内共享资源。Jamieson博士(TL),一位有成就的细胞免疫学家, 自2000年以来一直担任FCSR主任。自1988年以来担任FCSR经理的施密德女士 负责FCSR的日常运作,并协助Jamieson博士(TL)制定长期计划。两者都有 Jamieson博士(TL)和施密德女士可供用户咨询。为了实现其目标,FCSR 提供五个分析流式细胞仪、三个高速数字细胞分选器、一个AutoMACS细胞分离器和 一个独立的分析站。FCSR很容易访问,负责日常采购 所有仪器的校准、维护和维修。FCSR人员的年龄加起来为82岁 在流式细胞术方面的经验;他们的专业知识可以通过一对一咨询向调查人员提供, 课程、网站、海报演示文稿和开放参观。施密德女士和杰米森博士(TL)也在工作 让研究人员调整或开发分析方法,使研究人员能够在小说中提出研究问题 方式。FCSR服务帮助在流式细胞仪方面具有广泛经验的研究人员进行高性能 质量检测,耗费的时间最少。讲习班、研讨会和使用新的分析方法确保 研究人员保持在流式细胞术的前沿,而不需要投资自己的资金 资金或员工有时间跟上最新的进展。细胞检测仪器价格昂贵,而且 超出了大多数研究人员的个人预算;因此,FCSR提供了仪器以及 为研究人员节省额外的成本,通过获得赠款和机构支持来帮助抵消 购买、维护和操作这些工具。节省的成本将传递给 研究员。在上一次资助期间,共有254名调查人员使用了FCSR。在7月1日之间, 2006年至2007年6月30日(CCSG竞争性续签的报告期),JCCC成员 占总使用量的76%。这些数据客观地证明了FCSR在促进 加州大学洛杉矶分校的癌症研究及其对JCCC改进诊断、治疗和治愈的贡献 癌症患者。(另请参阅历史、描述、基本中关于共享资源的第6.2.3节 特征)。 代表11个癌症中心计划地区的86名癌症中心成员利用 报告所述期间的流式细胞仪共享资源。这是一个持续共享的资源。
英文摘要
The Flow Cytometry Shared Resource (FCSR) provides state-of-the-art analytical and sorting instrumentation as well as cutting-edge expertise, at an affordable cost, to UCLA investigators needing flow cytometry to pursue their research. The Jonsson Comprehensive Cancer Center (JCCC) established this campus-wide shared resource in 1988. Dr. Jamieson (Tl), an accomplished cellular immunologist, has been the Director of the FCSR since 2000. Ms. Schmid, the manager of the FCSR since 1988, is responsible for the daily operation of the FCSR and assists Dr. Jamieson (Tl) with long-term planning. Both Dr. Jamieson (Tl) and Ms. Schmid are available to users for consultation. To achieve its goals, the FCSR provides five analytic flow cytometers, three high-speed digital cell sorters, an AutoMACS cell separator and a free-standing analysis station. The FCSR is easily accessible and is responsible for procurement, daily calibration, maintenance and repair of all instrumentation. FCSR personnel have a combined 82 years of experience in flow cytometry; their expertise is available to investigators through one-on-one consultation, classes, a website, poster presentations and open houses. Ms. Schmid and Dr. Jamieson (Tl) also work with researchers to adapt, or develop, assays to enable investigators to pursue research questions in novel ways. FCSR services help researchers with a wide range of experience in flow cytometry to perform high quality assays, with minimal time expenditure. Workshops, seminars and utilization of new assays ensure that researchers remain on the cutting-edge of flow cytometry without the necessity of investing their own funds or staff time to keep current in the latest advances. Cytometric instrumentation is expensive and beyond the budget of most individual researchers; therefore, the FCSR provides instrumentation, as well as additional cost savings to researchers, by obtaining grant and institutional support to help offset the cost of purchasing, maintaining and operating those instruments. The cost savings are passed on to the researcher. During the last funding period, a total of 254 investigators used the FCSR. Between July 1, 2006, through June 30, 2007 (the reporting period for the CCSG competing renewal), JCCC members were responsible for 76% of the usage. These data objectively demonstrate the role of the FCSR in enhancing cancer research at UCLA and its contribution to JCCC's effort to improving diagnosis, therapy and cure of cancer patients. (Please also see Section 6.2.3 on Shared Resources in the History, Description, Essential Characteristics). 86 Cancer Center members representing 11 Cancer Center Program Areas utilized the services of the Flow Cytometry Shared Resource during the reporting period. This is a continuing shared resource.
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Durability of immune responses to SARS-CoV-2 infection in the context of HIV-infection, aging and cross-reactive immune responses.
  • 批准号:
    10188882
  • 项目类别:
  • 资助金额:
    $19.5万
  • 财政年份:
    2016
  • 负责人:
    Beth Deirdre Jamieson-Karavodin
  • 依托单位:
Characterizing the Epigenetic relationship between aging, HIV-infection, ART and biological outcomes
  • 批准号:
    9753079
  • 项目类别:
  • 资助金额:
    $69.63万
  • 财政年份:
    2016
  • 负责人:
    Beth Deirdre Jamieson-Karavodin
  • 依托单位:
Characterizing the Epigenetic relationship between aging, HIV-infection, ART and biological outcomes
  • 批准号:
    9065269
  • 项目类别:
  • 资助金额:
    $62.55万
  • 财政年份:
    2016
  • 负责人:
    Beth Deirdre Jamieson-Karavodin
  • 依托单位:
Cytometry Core
  • 批准号:
    8377981
  • 项目类别:
  • 资助金额:
    $16.31万
  • 财政年份:
    2012
  • 负责人:
    Beth Deirdre Jamieson-Karavodin
  • 依托单位:
海外基金