Clinical Managment and Trials Core and Advocacy Sub-Core

项目总结（见说明）： 胰腺癌UAB/UMN孢子临床管理和试验核心的总体目的 Cancer将在两个站点提供协调的基础设施和专业知识，以支持SPORE 研究人员将他们成熟的基础科学思想转化为临床方案。这将是 通过以下具体目标实现：（1）提供一个全面的，多学科的， 为所有胰腺癌患者提供患者护理临床路径。(2)为了便于临床翻译， 主要项目。(3)建立UAB/UMN联合胰腺癌临床数据库（PCCD）， 作为一个符合caBIG标准的数据库，然后可以链接到胰腺癌协作登记处 （PCCR）在内布拉斯加大学。(4)提供组织资源并与之协调， 分子病理学核心（组织核心）是根据组织病理学核心采集尿液、血清和组织。 现有临床方案并支持SPORE项目。(5)为转诊医生、患者、 和公众提供有关胰腺癌研究和临床方案的信息， UAB和UMN综合癌症中心，其他胰腺孢子，国家胰腺癌 协作登记处（PCCR）和其他医疗中心通过通讯，网站和社区 宣传委员会。(6)为少数研究者提供入选和参与的机会 通过与莫尔豪斯医学院的持续合作进行临床试验开发， 塔斯基吉大学，并在获得临床注册服务设施的协助下， （FACES）的UAB综合癌症中心（CCC）和国家生物伦理中心， 在塔斯基吉的研究和医疗保健。核心将由Selwyn M博士指导。维克斯，谁会 在联席总监C博士的领导下，沿着核心的全面领导和管理。 Mel Wilcox，在其重要组成部分之间进行协调，包括UAB多学科 胃肠肿瘤诊所（MDGI）和UMN胰腺和肝脏中心（PLC）。此外 宣传分核心将通过参与胰腺癌支持发挥不可或缺的作用 小组、患者和家庭教育以及社区对胰腺癌的认识。

PROJECT SUMMARY (See instructions): The overall purpose of the Clinical Management and Trials Core of the UAB/UMN SPORE in Pancreatic Cancer is to provide a coordinated infrastructure and expertise at both sites to support SPORE investigators in translation of their mature basic science ideas into clinical protocols. This will be accomplished through the following speciflc aims: (1) To provide a comprehensive, multi-disciplinary, patient care clinical pathway for all patients with pancreatic cancer. (2) To facilitate the clinical translation of SPORE major projects. (3) To establish the Joint UAB/UMN Pancreatic Cancer Clinical Database (PCCD), as a caBIG compliant database which can then be linked to the Pancreatic Cancer Collaborative Registry (PCCR) at the University of Nebraska. (4) To provide and coordinate with the Tissue Resource and Molecular Pathology Core (Tissue Core) the acquisition of urine, serum, and tissue according to the existing clinical protocol and in support of SPORE projects. (5) To provide referring physicians, patients, and the public with information regarding pancreatic cancer research and clinical protocols available at UAB and UMN Comprehensive Cancer Centers, other Pancreatic SPORES, the national Pancreas Cancer Collaborative Registry (PCCR), and other Medical Centers via newsletter, web sites, and the Community Advocacy Board. (6) To provide the opportunity for minority Investigator inclusion and participation in clinical trial development through continued partnerships with the Morehouse School of Medicine and Tuskegee University, and with the assistance of the Facility for Access to Clinical Enrollment Services (FACES) of the UAB Comprehensive Cancer Center (CCC) and the National Center for Bioethics in Research and Healthcare at Tuskegee. The Core will be directed by Dr. Selwyn M. Vickers who will provide overall leadership and administration of the Core, along with the leadership of Co-Director Dr. C. Mel Wilcox, in coordination among its essential components including the UAB Multidisciplinary Gastrointestinal Oncology Clinic (MDGI) and the UMN Pancreas and Liver Center (PLC). In addition the Advocacy Sub-Core will play an integral role through involvement with the pancreatic cancer support group, patient and family education, and community awareness for pancreatic cancer.