Foot Infrared Rolling Scan Transducer (FIRST)

脚部红外滚动扫描传感器（FIRST）将执行可见/近红外（NIR）光谱成像来量化脱氧血红蛋白（脱氧- hb）和氧合血红蛋白（氧合- hb）的水平，这表明皮肤水肿、红斑和微循环丧失的可能性。这种手持设备将用于日常足部自我检查，以鼓励糖尿病患者评估可能导致溃疡发生的潜在皮肤破裂问题。重点是提供潜在溃疡的早期评估和纠正治疗（即患者个人活动的剂量），以防止皮肤破裂。体内监测将作为三波长测量来评估足部组织中脱氧血红蛋白和脱氧血红蛋白吸收的变化。光将通过一个滚动扫描器头投射到病人的脚上，专用的光探测器将在光与组织相互作用后接收到光。

DESCRIPTION (provided by applicant): FIRST The Foot Infrared Rolling Scan Transducer (FIRST) will perform visible/near- infrared (NIR) spectral imaging to quantify the levels of deoxygenated hemoglobin (deoxy-Hb) and oxygenated hemoglobin (oxy-Hb) that indicate potential for cutaneous edema, erythema, and microcirculation loss. The hand- held device will be used during daily foot self-exams to encourage diabetic patients to assess potential skin breakdown problems that can cause ulceration to occur. The key focus is to provide early assessment of potential ulceration and corrective treatment (i.e. dosage of patient personal activity) to prevent skin breakdown. In vivo monitoring will be performed as a triple wavelength measurement assessing changes in absorption of deoxy-Hb and oxy-Hb in foot tissue. Light will be projected into the patient's foot through a rolling scanner head and dedicated light detectors will receive the light after it has interacted with the tissue. PUBLIC HEALTH RELEVANCE: FIRST The key focus is to provide early assessment of potential ulceration and corrective treatment (i.e. dosage of patient personal activity) to prevent skin breakdown. In vivo monitoring will be performed as a triple wavelength measurement assessing changes in absorption of deoxy-Hb and oxy-Hb in foot tissue.