Immunology Physician Scientist

描述(由申请人提供)：这是NIH T32机构培训补助金的新申请，用于培训北岸LIJ卫生系统内范斯坦医学研究所的医生和科学家在免疫介导性疾病方面的研究。庞大的申请者池(过敏和免疫学住院医师培训计划每年110英镑)是优秀医生候选人的来源，可以培训为免疫学学科的研究人员。这些候选人将被竞争性地选入T32培训计划，接受为期3年的严格科学培训。基于他们在研究和教学方面的卓越表现，16名老牌范斯坦学院的研究人员被精心挑选出来担任导师。学员将在范斯坦研究所的Elmezzi研究生院注册课程，以获得免疫学、遗传学和基因组学以及临床和翻译研究原理方面的全面知识基金。他们将在编写和出版手稿、在国家会议上作口头陈述、准备赠款申请方面接受指导，并将在发展调查职业方面得到协助。范斯坦研究所提供了一个高度互动的关键研究人员群体，其中包括Elmezzi学院的研究生、医学院学生(纽约大学阿尔伯特·爱因斯坦医学院)、博士生和医学博士/博士生。导师将提供3个主题领域的培训机会：1)自身免疫和免疫反应，2)遗传和疾病发病机制，3)炎症和宿主对感染的反应。这些导师在临床和转化性研究中提供深入和多样化的免疫介导性疾病暴露。这一T32培训计划的目标是培养免疫学内科医生和科学家，他们将担任未来的研究人员领导，吸引和保持代表性不足的少数族裔，并满足全国对免疫学研究人员的需求。它的独特性是致力于并成功地改变临床实践，这是导师的特点。 相关性：内科科学家人数的减少是一个严重的问题。需要训练有素的完成免疫学培训计划的个人，以保持生物医学研究新的和创造性的进展的快速步伐，以加强对免疫和炎症性疾病患者的护理。这些疾病仅在美国就影响了超过1.5亿人，每年造成超过1000亿美元的损失。这一新的培训计划致力于成功应对这一重要挑战。

DESCRIPTION (provided by applicant): This is a new application for a NIH T32 institutional training grant for training Physician-Scientists in research in immune-mediated disease at The Feinstein Institute for Medical Research within the North Shore LIJ Health System. The large applicant pool (>110 per year for the Allergy and Immunology Residency Training Program) is a source of outstanding physician candidates to train as investigators in the discipline of immunology. These candidates will be competitively selected for appointment to the T32 training program for 3 years of rigorous scientific training. Sixteen established Feinstein faculty investigators have been carefully selected to serve as mentors, based on their excellence in research and teaching. Trainees will enroll in courses at the Elmezzi Graduate School at the Feinstein Institute to acquire a comprehensive fund of knowledge in immunology, genetics and genomics, and the principles of clinical and translational research. They will receive instruction in the preparation and publication of manuscripts, oral presentations at national meetings, preparation of grant applications, and will be assisted in the development of an investigative career. The Feinstein Institute provides a highly interactive critical mass of investigators with diverse trainees comprised of graduate students in the Elmezzi School, medical students (Albert Einstein College of Medicine, NYU), PhD fellows and MD/PhD fellows. Mentors will provide training opportunities in 3 thematic areas: 1) autoimmunity and immune responsiveness, 2) genetic and disease pathogenesis, and 3) inflammation and host response to infection. These mentors provide an in depth and diverse exposure to immune-mediated diseases at the bench in clinical and translational studies. The goal of this T32 training program is to develop immunology physician-scientists who will serve as future investigator leaders, attract and maintain underrepresented minorities, and address the national need for immunology investigators. Its uniqueness is the commitment to and success at transforming clinical practice that characterizes the mentors. RELEVANCE: The decline in physician-scientists is a serious concern. Highly trained individuals completing training programs in immunology are needed to maintain the rapid pace of novel and creative advances in biomedical research that enhance the care of patients with immunologic and inflammatory disorders. These disorders, in aggregate affect over 150 million individuals in the U.S. alone, at a cost of over $100 billion annually. This new training program is committed to successfully respond to this important challenge.