Data Analysis and Coordinating Center (DACC) for Research Training Activities

产品说明：（申请人提供）：国家人类基因组研究所发起了一系列关于基因组学和伦理、法律的和社会问题的研究培训活动，其中包括研究培训联合会，重点是提高代表不足的少数群体个人的成功参与。虽然各受赠方都参与评价和跟踪其方案实现目标的进展情况，但这并没有系统地进行，因此难以比较和汇集各方案的数据。RFA-HG-08-006的主要目标是建立一个数据分析和协调中心（DACC），以促进和简化整个MAP计划的评估和跟踪部分。圣路易斯华盛顿大学的一个跨学科研究小组在与RFA直接相关的领域具有相当大的优势和经验，正在提交本申请以回应RFA。本着实现RFA目标的强烈承诺，我们提出了4个具体目标：首先，我们将在审查每个培训中心目前实施的评估和跟踪工具后，为整个RTC开发补充评估和跟踪工具。其次，我们将创建一个基于Web的数据输入系统（DES）。已经为我们的一个暑期学院创建了一个原型，用于建立一个集中的数据库，用于存放来自受赠者的RTC数据，这些数据将成为所有数据分析的来源。第三，我们将使用标准方法定期对数据进行严格分析，并生成评估进展和成果的报告，在受赠者和培训协调员的年度会议以及NHGRI国家咨询理事会的半年期会议上报告调查结果，并定期提供书面报告。第四，我们将在其他领域提供必要的领导，这可能是通常对协调中心的期望，并与RTC和NHGRI密切合作，以实现RFA的目标。我们相信，我们拥有优势和经验，以及“人际交往能力”和对RFA目标的熟悉，但由于我们不直接隶属于任何研究培训中心，因此我们带来了新鲜感，客观性和灵活性。 公共卫生相关性：国家人类基因组研究所发起了一系列基因组学和伦理、法律的和社会问题方面的研究培训活动，重点是增加代表不足的少数群体的个人的成功参与。该数据分析和协调中心将促进和支持一个系统的评估和跟踪计划，以评估NHGRI是否以及在多大程度上正在朝着其增加URM个人数量的目标前进。

DESCRIPTION: (provided by applicant): The National Human Genome Research Institute (NHGRI) has launched a series of research training activities in Genomics and Ethical, Legal, and Social Issues (ELSI), comprising the Research Training Consortium (RTC), with a focus on increasing the successful participation of individuals from Under Represented Minorities (URM). While the various grantees are involved in evaluating and tracking progress towards their goals for their own programs, this has not been done systematically, making it difficult to compare and pool data across programs. The major goal of RFA-HG-08-006 is to establish a Data Analysis and Coordinating Center (DACC) to facilitate and streamline the evaluation and tracking component for the entire MAP initiative. An interdisciplinary team of investigators with considerable strengths and experience in areas of direct relevance to the RFA from Washington University in St. Louis is submitting this application in response to the RFA. With a strong sense of commitment to accomplish the goals of the RFA, we propose 4 specific aims: First, we will develop complementary evaluation and tracking tools for the entire RTC after reviewing the evaluation and tracking instruments currently implemented within each of the training centers. Second, we will create a web-based Data Entry System (DES). a prototype of which has already been created for one of our Summer Institutes, for establishing a centralized database for deposition of the RTC data from grantees that will become the source of all data analysis. Third, we will periodically perform rigorous analyses of the data using standard methods and generate reports that would assess progress and outcomes, report the findings at annual meetings of the grantees and training coordinators and bi-annual meetings of the National Advisory Council of the NHGRI, and provide written reports periodically. Fourth, we will provide leadership as necessary in other areas as maybe customarily expected of coordinating centers and work closely with the RTC and the NHGRI in achieving the goals of the RFA. We believe that we have the strengths and experience as well as the "people skills" and familiarity with the RFA goals and yet we bring a sense of freshness, objectivity, and flexibility to the table by virtue of not being directly affiliated with any of the research training centers. PUBLIC HEALTH RELEVANCE: The National Human Genome Research Institute (NHGRI) has launched a series of research training activities in Genomics and Ethical, Legal, and Social Issues, with a focus on increasing the successful participation of individuals from Under Represented Minorities (URM). This Data Analysis and Coordinating Center will facilitate and support a systematic evaluation and tracking program to assess whether and to what extent the NHGRI is progressing toward its goal of increasing the number of individuals of URMs.