CORE 1: OPERATIONS AND CLINICAL ASSESSMENT

该申请要求五年的支持，以建立一个NIMH干预发展中心 和题为“精神分裂症进展的脆弱性”的应用研究（“CIDAR”）。的操作 和临床评估（OCA）核心（Seidman，PI）负责研究的位置和招募 参与者，选择所有临床（例如，诊断和神经心理学）仪器、培训和质量 控制仪器的使用，监督招聘人员、诊断人员、评级人员和测试人员。的 OCA负责维护受试者流程，维护研究参与者的所有记录， 确保遵循IRB、HIPAA和其他监管程序。亚奥理事会还负责 数据管理和统计分析。亚奥理事会是一项复杂研究的运作中心， 其他

This application requests five years of support to establish an NIMH Center for Intervention Development and Applied Research ("CIDAR") entitled "Vulnerability to Progression in Schizophrenia". The Operations and Clinical Assessment (OCA) Core (Seidman, PI) is responsible for location and recruitment of research participants, selection of all clinical (e.g., diagnostic and neuropsychological) instruments, training and quality control of the use of the instruments, and supervision of recruiters, diagnosticians, raters and of testers. The OCA is responsible for maintaining the subject flow, maintaining all records of study participants and ensuring that IRB, HIPAA and other regulatory procedures are followed. The OCA is also responsible for data management and statistical analysis. The OCA is the operational hub of a complex study involving five other