Freezing of Gait: From clinical phenomena to basic mechanisms of gait and balance

描述（由申请人提供）： 步态冻结（FoG）是帕金森病患者的常见问题，可导致活动能力丧失、福尔斯和生活质量下降。FoG是神秘的，临床现象没有充分的特点，病理生理学未知，经验性治疗很大程度上无效。这次关于FoG的研讨会的目标是增加对FoG的理解，并激发对这一现象的兴趣和研究。最终目标是更好地治疗FoG患者。对FoG感兴趣的临床医生和对运动控制，平衡和运动感兴趣的基础科学家将聚集在一起，研究FoG的临床现象学，探索可能与FoG相关的平衡和运动的基本生理机制，并探索FoG发病机制的许多假设。由于研讨会规模较小，出席人数有限，会议的主要成果将是对该主题的一个或多个综述，这将是该主题的第一次综述，并且将是与FoG相关的“临床和基础科学状况”。

DESCRIPTION (provided by applicant): Freezing of gait (FoG) is a common problem in people with Parkinson's disease and causes loss of mobility, falls and decreased quality of life. FoG is mysterious, the clinical phenomenon not fully characterized, the pathophysiology unknown and empirical treatment largely ineffective. The goal of this workshop on FoG is to increase understanding of FoG and to stimulate interest and research on the phenomenon. The ultimate goal is better treatment for patients with FoG. Clinicians interested in FoG and basic scientists interested in motor control, balance and locomotion will gather to examine the clinical phenomenology of FoG, explore basic physiological mechanisms of balance and locomotion that might relate to FoG and to explore the many hypotheses as to the pathogenesis of FoG. Because the workshop will be small with limited attendance, the major outcome of the meeting will be one or more reviews of the topic that will be the first review(s) on this topic and will be a "state of the clinical and basic science" relevant to FoG.