Adolescent Medicine Trials Network for HIV/AIDS Interventions

洛杉矶儿童医院(CHLA)的使命是“促进儿童的健康和福祉 通过整合医疗保健、预防服务、医学教育和研究 在爱、同情和尊重他人的氛围中，回应我们社区的需求。 自20世纪80年代初以来，中华医学会青少年医学部一直专注于降低青少年感染风险 通过与联合国儿童基金会合作建立的创新服务、研究和培训模式，帮助青年 社区。通过这些方案，该司提供保健、精神健康、病例管理、 每年向9000多名青少年提供健康教育和药物滥用治疗服务，并参与 社区一级的怀孕、艾滋病毒和暴力预防干预措施。 自青少年试验网络(ATM)成立以来，CHLA已成为 生产青少年医学试验股(ATU)，为ATU在全球的主要任务做出贡献 在临床试验中招募和保留受试者，并产生高质量的数据。在……方面 行为试验，CHLA比任何其他ATM网站都有更多的参与和招募。对于社区而言 预防试验(Connect To Protected)，CHLA是(15个网站中)首批完成索引的三个网站之一 访谈，并开始简短的基于地点的调查。至于治疗试验，CHLA一直在 招聘人数排在前三分之一。我们网站管理的质量反映在持续的积极评价中 在我们每半年一次的现场考察中。 洛杉矶ATU不仅确立了自己作为一个富有成效的ATU的地位，而且还为 ATM通过积极参与委员会和开发新的行为规范。该网站 在本项目的所有五年中，Pi一直担任ATU主席，并在执行和现场表演中担任职务 委员会。此外，CHLA是少数几个启动ATN协议(ATN 039)的ATU站点之一。 CHLA目前正在制定另一项涉及使用手机的原始协议 作为对解决不遵守规定问题的提醒。 以下申请文件由洛杉矶儿童医院(CHLA)分部 青少年医学具有作为网站参与所需的经验、专业知识和基础设施 ATN。我们的核心人员计划将使我们能够继续有效地招聘和留住 治疗、行为和社区试验。此外，我们经验丰富的员工将继续积极参与 新议定书的制定，从而使我们能够继续为ATN科学议程作出贡献。 ATN研究议程与公共卫生特别相关，因为它将对我们的 青少年对艾滋病毒的了解。

The mission of Childrens Hospital Los Angeles (CHLA) is "to advance the health and well-being of children and adolescents by integrating medical care, preventive services, medical education, and research in response to the needs of our community and in an atmosphere of love, compassion, and respect for people." Since the early 1980's, the Division of Adolescent Medicine at CHLA has focused on reducing risks for young people through innovative models of service, research and training established in partnership with the community. Through these programs, the Division provides health care, mental health, case management, health education, and substance abuse treatment services to over 9000 youth annually, and is involved in community-level interventions for pregnancy, HIV, and violence prevention. Since the inception of the Adolescent Trials Network (ATM), CHLA has established itself as a productive Adolescent Medicine Trials Unit (ATU), contributing to the primary mission of the ATUs in the recruitment and retention of subjects in clinical trials and production of high quality data. In the area of behavioral trials, CHLA has far greater participation and recruitment than any other ATM site. For community prevention trials (Connect to Protect¿), CHLA is one of the first three (of fifteen) sites to complete the index interviews and begin the brief venue based surveys. As for therapeutic trials, CHLA has consistently been in the top third for recruitment. The quality of our site management is reflected in consistently positive reviews at our semi-annual site visits. The Los Angeles ATU has not only established itself as a productive ATU, but has contributed to the ATM through active involvement in committees and the development of new behavioral protocols. The site PI has been the ATU chair for all five years of this project and served on the Executive and Site performance committees. In addition, CHLA is one of the few ATU sites to have initiated an ATN protocol (ATN 039). CHLA is currently in the process of developing yet another original protocol involving the use of cell phones as reminders to address non-adherence. The following application documents that Childrens Hospital Los Angeles (CHLA), Division of Adolescent Medicine has the experience, expertise and infrastructure necessary to participate as a site in the ATN. Our core staffing plans will allow us to continue effective recruitment and retention into therapeutic, behavioral and community trials. In addition our experienced staff will continue to be active in the development of new protocols and thus allow us to continue to contribute to the ATN scientific agenda. The ATN research agenda is of particular relevance to public health, as it will significantly contribute to our understanding of HIV in adolescents.