Cardiovasology

说明（由申请人提供）：修订后的申请是要求继续资助31-35年的“血管学”培训计划。该计划已成功地完成了其使命，准备医生和非医生科学家在心血管医学和生物学的独立研究事业。受训人员在发表高质量的同行评审论文方面表现出色，并建立了赠款申请和学术安置的跟踪记录。所有的职位都是由有才华的MD和PhD候选人填补的。马约诊所为基础、临床和人群心血管科学培训提供了一个出色的环境，以人类疾病为中心主题。成就包括强大的学员招聘和保留，与优秀教师的互动指导，强大的组织结构和有利的环境，产生富有成效的学术生涯。建立在卓越的传统，更新是为了满足最高的教育标准，并提供尖端的博士后培训。课程是定制的，以匹配每个受训者的背景和职业道路。心力衰竭、缺血性心脏病和心律失常等疾病主题是培训的重点，反映了国家发病率和死亡率趋势。致力于NHLBI计划的重点，修订后的应用程序集成了国家的最先进的技术，一个全面的课程，以实现从板凳到床边的科学需求不断变化的领域的能力，并在研究生存技能的教学和实践指导多学科培训。该计划汇集了基础科学家，临床研究人员和人口科学家的协作团队，具有互补的专业知识。为了响应NIH研究科的建议，重新提交纳入了一个新的研究员到教师职业发展计划，建立以促进学员提前过渡到独立的教师地位，并实施了一个增强的少数民族招聘计划，以增加少数民族的人数谁接受培训。该计划利用有利的技术平台，并在马约诊所，导致硕士/博士学位学位授予计划。获得基因组学，蛋白质组学，代谢组学和生物信息学的技能，应用于心脏病的研究，是至关重要的，为明天的生物医学准备学员。新的产品包括遗传流行病学和医学信息学;药物基因组学;计算生物学;纳米医学;和基于细胞的疗法。修订后的申请强调了“心血管学”培训计划的愿景，以提供最先进的培训，吸引和指导医生科学家和基础研究人员，他们将成为心血管研究生物学和医学的领导先锋。

Description (provided by applicant): The revised application is a request for continuation of funding for years 31-35 of the "Cardiovasology" Training Program. This Program has successfully accomplished its mission in preparing physicians and nonphysician scientists for independent research careers in cardiovascular medicine and biology. Trainees have excelled in publishing high quality peer-reviewed papers, and have established a track-record of grant applications and academic placement. All slots were filled, in each of the awarded years, by talented MD and PhD candidates. Mayo Clinic has provided an outstanding environment for training in basic, clinical and population cardiovascular sciences with human disease as the central theme. Accomplishments include strong trainee recruitment and retention, interactive mentoring with outstanding faculty, robust organizational structure, and conducive environment, yielding productive academic careers. Building on a tradition of excellence, the renewal is developed to meet the highest educational standards, and offer cutting-edge postdoctoral training. The curriculum is customized to match the background and career path of each trainee. The disease theme of heart failure, ischemic heart disease and heart rhythm disorders is the focus of training, reflecting national morbidity and mortality trends. Committed to NHLBI programmatic emphases, the revised application integrates multidisciplinary training in state-of-the-art technologies, a comprehensive curriculum to achieve competencies in evolving areas of scientific need from the bench to the bedside, and didactic and practical instruction in research survival skills. The Program brings together a collaborative team of basic scientists, clinical investigators and population scientists with complementary expertise. In response to NIH Study Section recommendations, the resubmission incorporates a new fellow-to-faculty career development program established to foster an earlier transition of trainees into independent faculty status, and an enhanced minority recruitment plan implemented to increase the number of minority individuals who receive training. The Program capitalizes on enabling technological platforms, and degree-granting programs at the Mayo Clinic that lead to master/doctorate degrees. Acquisition of skills in genomics, proteomics, metabolomics and bioinformatics, applied to the study of heart disease, is paramount to preparing trainees for the biomedicine of tomorrow. New offerings include genetic epidemiology and medical informatics; pharmacogenomics; computational biology; nanomedicine; and cell-based therapies. The revised application underscores the vision of the "Cardiovasology" Training Program to provide most advanced training, attracting and mentoring physician-scientists and fundamental investigators who will comprise the vanguard of leadership in the biology and medicine of cardiovascular research.