A Multi-State Study of Cancer Treatment and Outcomes Among American Indians

描述（由申请人提供）：由于准入障碍和社会经济障碍，许多患有癌症的美洲印第安人和阿拉斯加原住民（AIAN）面临无法完成推荐治疗的风险。尽管存在这些担忧，但对AIAN伴癌症的治疗和结局知之甚少。AIAN癌症结局研究的重要障碍源于任何特定地区AIAN癌症患者的比例相对较小，以及个人数据库的范围有限。作为回应，我们建议将来自多个州和数据库的联合收割机信息结合起来，建立一个综合资源，用于评估诊断为肺癌、乳腺癌、结直肠癌、宫颈癌、前列腺癌和卵巢癌的AIAN的护理和结局。要创建此资源，我们将链接来自印第安人健康服务、州癌症登记处以及加州、俄勒冈州和华盛顿州AIAN癌症患者的医疗补助和医疗保险登记和索赔的患者记录。此外，为了确定不容易从行政记录中识别的潜在护理障碍，我们将对俄勒冈州和华盛顿州的AIAN癌症幸存者及其护理人员进行访谈。这些访谈将侧重于对癌症和癌症护理的态度，提供者与患者的误解，患者的不信任或误解，文化不敏感以及种族主义和歧视。弗雷德哈钦森癌症研究中心、所有三个州的医疗补助计划以及两个部落健康委员会与部落流行病学中心之间的密切合作关系大大增强了我们的研究--一个在西北波特兰地区印第安人健康委员会主持，另一个在加州农村印第安人健康委员会、滨江圣贝纳迪诺县印第安人健康公司、和印度卫生理事会公司

DESCRIPTION (provided by applicant): Due to access barriers and socioeconomic obstacles, many American Indians and Alaska Natives (AIAN) with cancer are at risk for not completing recommended therapy. Despite these concerns, little is known about treatment and outcomes for AIAN with cancer. Important barriers to cancer outcomes research for AIAN stems from the relatively small proportion of AIAN cancer patients in any particular region, and limited scope of individual databases. In response, we propose to combine information from multiple states and databases to build a comprehensive resource for evaluating care and outcomes for AIAN diagnosed with lung, breast, colorectal, cervical, prostate, and ovarian cancer. To create this resource, we will link patient records from the Indian Health Service, state cancer registries, and Medicaid and Medicare enrollment and claims for AIAN cancer patients in California, Oregon, and Washington State. In addition, to identify potential barriers to care that are not easily recognized from administrative records, we will conduct interviews of AIAN cancer survivors and their caregivers in Oregon and Washington State. These interviews will focus on attitudes towards cancer and cancer care, provider-patient miscommunication, patient mistrust or misperceptions, cultural insensitivity, and racism and discrimination. Our study is greatly enhanced by the close working partnerships among the Fred Hutchinson Cancer Research Center, the Medicaid programs of all three states, and two tribal health boards with tribal epidemiology centers-one hosted at the Northwest Portland Area Indian Health Board, and the other a partnership among the California Rural Indian Health Board, the Riverside San Bernardino County Indian Health Inc., and the Indian Health Council Inc.