Multidisciplinary Schizophrenia Research Training

描述（由申请人提供）：这是马里兰州精神病学研究中心（MPRC）首次竞争性更新T32培训补助金的重新提交，最初于2003年资助（MH 067533）。拟议计划的目标是准备MD，博士和PharmDs感兴趣的基础或临床研究的职业生涯在精神分裂症的转化研究。MPRC是马里兰州医学院精神病学系的一个部门，是一个专注于精神分裂症研究的中心，位于斯普林格罗夫医院中心，一家位于巴尔的摩外的住院精神健康医院。MPRC的教师有一个临床和神经科学研究的综合研究计划，涉及神经生理学，发育起源，家族关系，症状，神经认知和精神分裂症的治疗。这个成功的研究项目的特点是MPRC和附近SOM校园内不同临床前和临床研究人员之间的频繁互动和合作。在这个T32奖学金下提供的博士后培训主要集中在基础神经科学或精神分裂症的临床研究。所有学员都接受了MPRC的翻译观点的教育，并在精神分裂症的临床和神经科学方面提供了导师和教学培训。重新提交竞争性五年期续延申请的提议是每年资助3个新的受训人员职位，每个职位的研究金为期2年。虽然这是一个非常年轻的T32计划，但它在招募和培训独立研究人员方面是成功的。在最初供资期间，招收了10名受训人员。4名受训人员完成了培训方案，1人因个人原因退出，5人目前正在接受培训。在完成的4名教师中，有3名教师被任命为助理教授（马里兰州巴尔的摩大学，威尔士大学，班戈尔和奥斯纳布吕克大学），一名目前受雇于MPRC担任研究助理。其中三名毕业生获得了竞争性资助。目前的一名实习生将于7月从该项目毕业，并已获得马里兰州巴尔的摩大学的助理教授职位。此外，目前5名受训人员中有2人获得了竞争性的南亚干旱和荒漠化研究所青年调查员奖。 公共卫生相关性：像精神分裂症这样的复杂问题需要一个多学科的临床研究队伍，习惯于在综合团队中工作。该提案旨在通过招募和指导临床和临床前博士后来解决研究严重精神疾病的翻译科学家数量减少的问题。

DESCRIPTION (provided by applicant): This is a resubmission of the first competitive renewal of a T32 training grant at the Maryland Psychiatric Research Center (MPRC), originally funded in 2003 (MH067533). The goal of the proposed program is to prepare MDs, PhDs and PharmDs interested in basic or clinical research for a career in translational research in schizophrenia. The MPRC, a division of the University Of Maryland Medical School Department Of Psychiatry, is a focused center for schizophrenia research, located on the grounds of the Spring Grove Hospital Center, an inpatient mental health hospital located just outside Baltimore. The faculty of the MPRC have an integrated research program of clinical and neuroscience research into the neurophysiology, developmental origins, familial associations, symptoms, neurocognition, and treatment of schizophrenia. This successful research program is characterized by frequent interaction and collaboration among different preclinical and clinical researchers within the MPRC and nearby SOM campus. Postdoctoral training offered under this T32 fellowship has a primary focus on either basic neuroscience or clinical investigations of schizophrenia. All trainees are educated on the translational perspective of the MPRC and provided mentors and didactic training in both clinical and neuroscience in schizophrenia. This resubmission for a competitive five-year renewal application proposes to fund 3 new trainee positions in each year, with each a fellowship lasting for 2 years. Although this is a very young T32 program, it is successful in terms of recruiting and training independent researchers. During the initial funding period, 10 trainees were enrolled. Four trainees completed the training program, 1 withdrew for personal reasons and 5 are currently in training. Of the 4 that completed, 3 have faculty appointments at the Assistant Professor level (at the University of Maryland Baltimore, University of Wales, Bangor, and the University of Osnabruck) and one is currently employed at the MPRC as research associate. Three of these graduates have received competitive funding. One current trainee will graduate from this program in July and has secured an assistant professorship position at the University of Maryland Baltimore. In addition, 2 of the 5 current trainees have received competitive NARSAD Young Investigator awards. PUBLIC HEALTH RELEVANCE: Complex problems such as schizophrenia require a multidisciplinary clinical research workforce, accustomed to working in integrated teams. This proposal seeks to address the dwindling number of translational scientists studying severe mental illness by recruiting and mentoring clinical and preclinical post-docs.