Enhancing Inderdisciplinary Research in Aging and Age-Related Disease.

描述（由申请人提供）：在发达国家，衰老是疾病的最大单一风险因素。美国人口正在发生的人口结构变化大大增加了面临社会和经济上重大的年龄相关疾病风险的人口比例。与年龄有关的疾病日益成为国家紧急情况，可能会破坏《美国复苏和再投资法》（ARRA， 2009年）的长期效益。该P30提案通过创建一个新的研究小组来实现ARRA的目标，该小组预计将在四年内从3人增加到6人。这个新的研究小组将与地质科学跨学科研究联盟合作，并大大加强其活动；一组旨在了解年龄相关疾病中衰老成分的研究项目。新的研究将进行“衰老与疾病的跨学科培训”或“转化研究”或“炎症生物学”。资助该应用程序将加速科学的进步，为开发与年龄有关的疾病的有效疗法提供必要的知识，这是一个对国家经济福祉至关重要的领域。

DESCRIPTION (provided by applicant): Aging is the single largest risk factor for disease in developed countries. The ongoing demographic change in the American population is greatly increasing the proportion of the population at risk for socially and economically significant age-related diseases. Age-related diseases increasingly represent a national emergency, one that may undermine the long-term benefits of the American Recovery and Reinvestment Act of (ARRA, 2009). This P30 proposal addresses the goals of the ARRA by creating a new research group predicted to grow from three to six personnel over four years. This new research group will collaborate with and significantly enhance the activities of the Interdisciplinary Research Consortium on Geroscience; a group of research projects aiming at understanding the aging component in age-related disease. The new research will have "interdisciplinary training in aging and disease" or "translational research" or "inflammation biology". Funding the application will accelerate the progress of science that provides essential knowledge for the development of effective therapies for age-related diseases, an area of vital to the economic wellbeing of the nation. PUBLIC HEALTH RELEVANCE: Change in the American population is greatly increasing the proportion of the population at risk for socially and economically significant age-related diseases. Age-related diseases increasingly represent a national emergency, one that may undermine the long-term benefits of the American Recovery and Reinvestment Act of (ARRA, 2009). This project will help accelerate the progress of science that provides essential knowledge for the development of effective therapies for age-related diseases, an area of vital to the economic wellbeing of the nation.