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Targeting Age-Activated Proinflammatory Chemokine Signaling by CCL2/11 to Enhance Skeletal Muscle Regeneration in Aging

Targeting Age-Activated Proinflammatory Chemokine Signaling by CCL2/11 to Enhance Skeletal Muscle Regeneration in Aging
通过 CCL2/11 靶向年龄激活的促炎趋化因子信号传导以增强衰老过程中的骨骼肌再生
批准号：
478877
负责人：
Soleimani Vahab D
金额：
$69.66万
依托单位：
CIUSSS de Centre-Ouest-de-l'Ile-de-Montral-Jewish General
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2023
资助国家：
加拿大
项目状态：
未结题
起止时间：
2023-03-01 至 2028-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=478877&lang=en
关键词：
Aging Cell Biology Muscle Atrophy Muscle Stem Cell Biology Regenerative Medicine Rejuvenation Single Cell Technologies Stem Cell Niche

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中文摘要
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英文摘要
Aging has a detrimental effect on the skeletal muscle function. Shifting age demographics have dramatically increased human lifespan over the past century. However, increased lifespan has also led to an epidemic of age-related degenerative diseases. Appro
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会议论文
Functional interactions between myogenic factors and REST/NRSF in regulation of heterochromatin during skeletal muscle regeneration
Molecular Regulation of Muscle Stem Cell Homeostasis
Canada Research Chair Tier 2
  • 批准号：
    315509
  • 项目类别：
  • 资助金额：
    $36.43万
  • 财政年份：
    2014
  • 负责人：
    Soleimani Vahab D
  • 依托单位：
    McGill University
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