Bridging Efficacy and Effectiveness in Drug Abuse Treatment

描述（由申请人提供）：本提案的总体目标是支持申请人作为药物滥用治疗干预开发领域的新独立研究精神病学家的持续发展。提交此K 02是为了继续申请人以K23开始的开发，这使他能够在该领域获得独立的研究支持。在过去五年中，申请人一直在成瘾性疾病领域进行治疗开发、流行病学和服务研究。通过K 02奖，申请人寻求深化这一工作，同时继续发展他的职业生涯。拟议的研究计划的统一主题是制定干预措施，以改善有和没有共同发生的疾病成瘾的结果。该方案的重点将是制定可在社区环境中使用的干预措施，从而弥合功效和有效性。K 02围绕三个项目展开。第一个项目“SMART：改善药物滥用诊所精神病合并症的检测和治疗”（DA 020783）的目标是制定一项干预措施，以解决社区诊所治疗合并症的关键障碍。由纽约州酒精和药物滥用服务办公室资助的第二个项目“病态赌博青少年治疗”的目标是为这一人群制定一个手册化的CBT。第三个项目“西班牙裔人的药物滥用”（DA 019606）旨在建立一个经验基础，为西班牙裔人制定预防和治疗方案。成瘾领域需要临床医生-研究人员，他们可以连接功效和有效性研究，该奖项将通过与这些领域的专家合作和培训，提高申请人成功开展这项工作所需方法的技能。申请人职业计划的其他组成部分包括行为干预策略，生物统计学和继续道德培训的高级培训。最后，申请人将为各种教育活动做出贡献，并承担越来越重要的指导角色。在申请机构的大力支持下，本申请中提议的活动的计划成果将是培养一名有能力规划和开展研究的科学家，将成瘾性疾病治疗的功效和有效性联系起来。

DESCRIPTION (provided by applicant): The overall aim of this proposal is to support the continuing development of the applicant as a newly independent research psychiatrist in the field of interventions development for drug abuse treatment. This K02 is submitted to continue the applicant's development initiated with a K23, which permitted him to obtain independent research support in this field. Over the last five years the applicant has been conducting studies of therapy development, epidemiology and services research in the area of addictive disorders. Through the K02 award, the applicant seeks to deepen this line of work while continuing the development of his career. The unifying theme of proposed program of research is the development of interventions to improve the outcome of addictions with and without co-occurring disorders. The emphasis of the program will be on development of interventions that can be used in community settings and, thus, bridge efficacy and effectiveness. This K02 is built around three projects. The goal of the first project, "SMART: Improving Detection and Treatment of Psychiatric Comorbidity in Substance Abuse Clinics" (DA020783), is to develop an intervention to address key barriers to the treatment of co-occurring disorders in community clinics. The goal of second project, "Treatment for Adolescents with Pathological Gambling" funded by the New York State Office of Alcohol and Substance Abuse Services, is the development of a manualized CBT for this population group. The third project "Substance Abuse in Hispanics" (DA019606) seeks to establish an empirical foundation to develop prevention and treatment programs for Hispanics. The field of addiction needs clinicians-researchers who can bridge efficacy and effectiveness research, and this award will permit enhancement of the applicant's skills in the methods necessary to successfully conduct this work, through collaboration and training with experts in these fields. Other components of the applicant's career plan include advanced training in behavioral intervention strategies, biostatistics and the continuation of ethics training. Finally, the applicant will contribute to various educational activities and assume a progressively more important mentoring role. The planned outcome of the activities proposed in this application, with the strong support of the applicant's institution, will be the development of a scientist capable of planning and conducting research that will bridge efficacy and effectiveness in the treatment of addictive disorders.