Network-Attached Biomedical Research Data Management System

描述(申请人提供)：我们申请资金购买企业级生物医学研究数据管理系统，包括存储区域网络(SAN)中144 TB的新硬盘空间，以及来自Quantum/EMC的新的800 TB容量数据备份系统。所要求的设备将与我们目前内部资助的研究数据存储系统集成，该系统具有BlueArc网络连接存储(NAS)服务器和85TB的磁盘存储。总而言之，这些升级将提供急需的容量扩展和新的灾难恢复功能，这些功能将显著提高主要用户的140多个由NIH资助的数据密集型研究项目的数据分析、数据安全和整体工作效率。范德比尔特现有的BlueArc系统自2004年以来一直在使用，并已进行了五次升级，以满足研究界不断扩大的需求。这个内部资助的系统非常成功，目前是6个主要研究中心的主要数据设施，并为数十名NIH赞助的研究人员提供服务。然而，范德比尔特国立卫生研究院资助的研究企业的大幅增长(范德比尔特是全国十大医学院中增长最快的)要求扩大能力和部署灾难恢复设备，而不仅仅是范德比尔特大学的内部资助能力。与目前的系统一样，所要求的设备将由范德比尔特的信息技术服务(ITS)部门管理。ITS拥有经过专门培训的员工，他们操作高性能的NAS、SAN和企业备份设施，部署和管理所需的研究网络基础设施，将服务扩展到校园内的关键研究设施，并将系统托管在受环境控制且安全严密的数据中心。每千兆字节的使用费已经并将继续支持设备的服务，该机构承诺弥补该仪器及其相关基础设施的必要支持和维护方面的任何潜在财务短缺。大学和医学中心计划进行一次重大的数据网络升级，以支持该项目，如果该项目获得资金的话。由于尖端生物医学研究固有的快速增长的数据存储需求带来的相关成本，我们一直无法跟上对数据扩展的需求。当前系统超额订阅，并且没有执行系统范围备份的机制。所有相关各方都明确认识到这是一种危险行为。但是，由于我们目前没有存储和备份数据的替代方案，而是呈指数级增长的85TB数据，我们被迫接受重大的、甚至可能是灾难性的妥协。所要求的仪器对于扭转这种情况至关重要，因为它提供了必要的数据扩展和可靠性，以充分支持我们在遗传学、结构生物学、质谱学、蛋白质组学、细胞和医学成像等领域的数据密集研究活动。

DESCRIPTION (provided by applicant): We request funds to purchase an enterprise-class biomedical research data management system consisting of 144 useable terabytes of new hard disk space in a storage area network (SAN), and a new 800 terabyte capacity data backup system from Quantum/EMC. This requested equipment will integrate with our current, internally funded research data storage system featuring a BlueArc network-attached storage (NAS) server and 85 terabytes of disk storage. Together, the upgrades will provide desperately needed capacity expansion and new disaster recovery capabilities that will dramatically improve data analysis, data security, and overall productivity for over 140 NIH-funded data-intensive research projects of the major users. Vanderbilt's existing BlueArc system has been in service since 2004 and has been upgraded five times in attempt to meet the expanding requirements of the research community. This internally funded system has been very successful, and currently is the primary data facility for 6 major research centers and cores serving of scores of NIH- sponsored investigators. However, the substantial rate of growth of Vanderbilt's NIH-funded research enterprise (Vanderbilt is the fastest growing of the top 10 medical schools in the country) calls for capacity expansion and deployment of disaster recovery equipment beyond the intramural funding capabilities of Vanderbilt University alone. As with the current system, the requested equipment will be managed by Vanderbilt's Information Technology Services (ITS) department. ITS has staff who are specially trained to operate high-performance NAS, SAN and enterprise backup facilities, deploy and manage the required research network infrastructure to extend the service to key research facilities around campus, and host the system in an environmentally-controlled and tightly secured data center. Per-gigabyte user fees have and will continue to support the service of the equipment, with the institution committed to covering any potential financial shortfalls for the necessary support and maintenance of this instrument and its associated infrastructure. A significant data network upgrade is planned by the University and Medical Center in support of this project should it be funded. Due to the costs associated with the rapidly expanding data storage requirements inherent in cutting-edge biomedical research, we have been unable to keep up with demand for data expansion. The current system is oversubscribed, and there is no mechanism to perform system-wide backups. All parties involved clearly recognize this as risky behavior. But with no alternative for storing and backing up our current, but exponentially growing 85 terabytes of data, we are forced to live with significant, even potentially catastrophic compromises. The requested instrumentation is critical to reversing this situation by providing the necessary data expansion and reliability to adequately support our data-intensive research activities in the areas of Genetics, Structural Biology, Mass Spectrometry, Proteomics, Cell and Medical Imaging, among others.