PACDI-DP: AN INTERVENTION FOR YOUTH AT RISK FOR DIABETES

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 在12个月时，评估两种强度的PACEI-DP(互联网糖尿病预防)干预对男性和女性青少年体重指数(BMI)的影响。BMI被认为是主要的结果，因为在ADA的“高风险”标准中，它可以通过体重控制和生活方式干预来改变。在6个月和12个月时评估干预对胰岛素抵抗代谢和生理表现的影响，包括空腹胰岛素、空腹血糖、血脂水平、微量白蛋白尿、黑棘皮病和血压。评估人体测量指标，以及饮食和体力活动的行为指标，包括总能量摄入量、来自膳食脂肪、纤维的卡路里百分比、食物消耗量、总能量消耗以及久坐行为/娱乐媒体使用。探索性目标将评估干预对心理社会调解人的影响，对父母体重指数的影响，评估对干预的满意度，并评估每次干预的健康结果、成本和成本效益。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Evaluate the effect, at 12 months, of the two intensities of the PACEi-DP (Pace-Internet for Diabetes Prevention) intervention on Body Mass Index (BMI) among male and female adolescents. BMI is proposed as the primary outcome because among the ADA "high risk" criteria, it is modifiable through weight control and lifestyle interventions. Assess at 6 and 12 months the impact of the intervention on metabolic and physiological manifestations of insulin resistance including fasting insulin, fasting blood glucose, blood lipid levels, microalbuminuria, acanthosis nigricans, and blood pressure. Assess anthropometric measures, and behavioral measures of diet and physical activity including total energy intake, percent calories from dietary fat, fiber, consumption of food, total energy expended and sedentary behaviors/recreational media use. Exploratory aims will assess the impact of the intervention on psychosocial mediators, impact on parents BMI, assess satisfaction with the intervention, and assess health outcomes, cost and cost-effectiveness of each intervention.