SMART: A Social and Mobile Weight Control Program for Young Adults

描述（由申请人提供）：体重增加和肥胖的问题是年轻人的重要问题。从青春期到成年早期，无论他们是否上大学，参军或高中毕业后进入劳动力市场，他们都会遇到多种压力和影响，从而导致体重增加。体重增加反过来又会增加患心血管疾病、糖尿病和其他健康问题的风险。在这一人群中，人们对如何干预防止体重增加或使体重减轻知之甚少。我们建议开展形成性研究，开发一种干预措施，社交/移动减肥方法（SMART），以防止体重增加并促进有体重增加风险的年轻人减肥。然后，我们将在406名参与者中进行一项随机对照试验，以评估SMART在12个月和24个月时对体重状况和其他代谢、行为和社会心理结果的影响。SMART将是一种基于理论的干预，将网络、移动电话和社交媒体组件结合成一个引人入胜的体重控制计划。该项目将建立在我们之前的干预研究工作的基础上，以改善与体重相关的行为和体重结果，以及基于手机的行为干预。我们将与斯坦福大学的研究人员合作，在圣地亚哥对SMART进行形成性研究。随后将开发最终的SMART软件架构和系统。然后进行为期2年的随机对照试验，评估SMART对体重相关结局的影响。该研究的主要目的是研究两组患者在24个月时体重状况（kg）的差异：a)基线体重正常的患者，以评估SMART对预防体重增加的支持程度；b)基线时超重/肥胖的参与者，评估其体重减轻情况。将在两组中招募足够数量的参与者来评估这些结果。该研究的次要和探索性目的将是检查与干预措施使用和满意度相关的其他健康相关结果和过程措施。相关性（见说明）：超重/肥胖在美国非常普遍，影响了大约66%的成年人。减少肥胖的总体发生率是一个主要的公共卫生问题，然而对于如何对年轻人做到这一点却知之甚少。这项研究将填补这一知识空白。（摘要结束）

DESCRIPTION (provided by applicant): The problem of weight gain and obesity is important in young adulthood. As individuals traverse life paths from adolescence into early adulthood, whether or not they attend college, join the military or enter the workforce out of high school, they encounter multiple stressors and influences that contribute to weight gain. Weight gain in turn leads to increase risk of cardiovascular disease, diabetes and other health problems. Little is known about how to intervene to prevent weight gain or enable weight loss in this population. We propose to conduct formative research to develop an intervention, Social/Mobile Approach to Reduce Weight (SMART) to prevent weight gain and promote weight loss in young adults at risk for weight gain. We will then conduct a randomized controlled trial in 406 participants to evaluate the effects on weight status and other metabolic, behavioral and psychosocial outcomes of SMART at 12 and 24 months. SMART will be a theory- based intervention that combines web, mobile phone and social media components into an engaging weight control program. The project will build on our prior work in intervention research to improve weight-related behaviors and weight outcomes and in mobile phone based behavioral interventions. We will perform formative research on SMART in San Diego and in collaboration with researchers at Stanford University. This will be followed by development of the final SMART software architecture and system. Then a 2-year randomized controlled trial will be conducted to evaluate the effects of SMART on weight-related outcomes. The primary aims of the study will be differences in weight status (kg) at 24 months among two groups: a) Those with a normal weight at baseline to evaluate how well SMART supports the prevention of weight gain; and b) Overweight/obese participants at baseline in whom weight loss will be evaluated. Sufficient numbers of participants in both groups will be recruited to evaluate these outcomes. Secondary and exploratory aims of the study will be to examine other health related outcomes and process measures related to intervention use and satisfaction. RELEVANCE (See instructions): Overweight/obesity are highly prevalent conditions in the US impacting approximately 66% of the adult population. Reducing the overall incidence of obesity is a major public health concern, yet little is known about how to do this with young adults. This study will address this gap in knowledge. (End of Abstract)