FRONTO-STRIATAL DYSFUNCTION AND COMPENSATORY MECHANISMS IN FRAGILE X

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 简介： 功能性磁共振成像（fMRI）研究表明，当脆性X综合征（FraX）患者执行执行功能任务时，神经活动异常。 具体目标： 研究这种异常活动的具体性质或尚未阐明的可能的代偿过程。 研究方法： 我们研究了大脑激活模式，使用功能磁共振成像在去/不去任务与FraX和控制的青少年男性。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Introduction: Functional magnetic resonance imaging (fMRI) studies have shown evidence of aberrant neural activity when individuals with fragile X syndrome (FraX) perform executive function tasks. Specific Aims: To investigate the specific nature of this aberrant activity or possible compensatory processes that has yet to be elucidated. Methods: We examined brain activation patterns using fMRI during a go/nogo task in adolescent males with FraX and in controls.