Dosing and Motor Learning in Children with an Injured Brain or Cerebral Palsy

描述(申请人提供)：建议的研究峰会的目的是促进制定大规模或多地点的研究建议，以解决患有脑损伤或脑瘫(CP)的儿童有效干预(剂量)的频率、强度和持续时间的阈值，并提高儿科物理治疗师的研究能力。我们将邀请跨学科的研究人员(物理治疗师、基础和临床科学家)、资助机构的代表和父母参加为期2.5天的密集智囊团。峰会的结构将是：提供对这一问题的理论科学概述，并结合这些儿童及其家庭在现实世界中的关切，将概念与制定科学问题和探索剂量的方法的实际问题相结合，并为这一领域的第二代研究优先事项制定行动计划。我们的理论是，对儿科物理治疗研究人员投入时间和培训将导致研究生产率的显着提高，并最终护理和治疗患有脑损伤或脑瘫的儿童。事实上，以前的峰会使用这些方法都是相当成功的。 公共卫生相关性：拟议项目的目标是干预的一个关键和更紧迫的方面，这对治疗效果和治疗如何影响残疾儿童的结果至关重要。它还针对物理治疗师研究人员，这是一个在儿科领域落后于其他研究人员的群体。对儿科理疗研究人员进行干预剂量、投入时间和培训等问题的跨学科方法不仅将显著提高研究效率，而且最终还将有助于护理和治疗患有脑损伤或脑瘫的儿童。

DESCRIPTION (provided by applicant): The purpose of the proposed research summit is to foster development of large scale or multi-site research proposals to address thresholds for effective frequency, intensity, and duration of interventions (dosing) for children with injured brains or cerebral palsy (CP) and to enhance the research capacity of pediatric physical therapists. We will invite an interdisciplinary cadre of researchers (physical therapists, basic- and clinical scientists), representatives from funding agencies, and parents to an intensive 2.5-day think-tank. The summit will be structured to: provide theoretical scientific overview of the problem juxtaposed with real-world concerns for these children and their families, integrate concepts with practical issues of formulating scientific questions and approaches to explore dosing, and develop action plans for second generation research priorities in this area. We theorize that investing time and training to pediatric physical therapy researchers will result in significant gains in research productivity and ultimately the care and treatment of children with injured brains or CP. Indeed previous summits, using these approaches have been quite successful. PUBLIC HEALTH RELEVANCE: The proposed project targets a critical and more pressing aspect of intervention that is pivotal to treatment efficacy and how treatments influence outcome in children with disabilities. It also targets physical therapist researchers, a group that lags behind other researchers in the area of pediatrics. The interdisciplinary approach to the problems of dosing of interventions and investing time and training to pediatric physical therapy researchers will not only result in significant gains in research productivity, but also ultimately in the care and treatment of children with injured brains or CP.